Browsing by Author "dd459282-1bb4-440d-8b86-5ebe2177d4df"
Now showing items 1-4 of 4
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Romero, Asunción; Miranda, Hugo F.; Puig, Margarita M. (2010)The purpose of the present study was to characterize the antinociceptive effects of tramadol, fentanyl and morphine, when two of them were systemically combined in a 1:1 potency ratio, in the hot plate, the acetic acid ...
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Miranda, Hugo F.; Romero, Maria Asunción; Puig, Margarita M. (2012)Preclinical studies have demonstrated antinociceptive synergism between dexketoprofen (DEX) and tramadol (TRM) in acute animal models of nociception. The aim of the present study was to investigate the type of interaction ...
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Romero, Asunción; Miranda, Hugo F.; Puig, Margarita M. (Elsevier Inc., 2010)The development of morphine-tolerance after chronic administration, reduces analgesic efficacy and is a significant clinical problem in some patients; may be managed clinically by increasing the doses of morphine and/or ...
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Miranda, Hugo F.; Puig, Margarita M.; Dursteler, Christian; Prieto, Juan Carlos; Pinardi, Gianni (2007)The antinociceptive activity of dexketoprofen was studied in mice using the acetic acid writhing test (acute tonic pain), the tail flick test (acute phasic pain) and the formalin assay (inflammatory pain). Isobolographic ...