Now showing items 1-10 of 10

    • Palma, Verónica; Kukuljan Padilla, Manuel; Mayor, Roberto (Cell Press, 2001)
      Calcium signals participate in the differentiation of electrically excitable and nonexcitable cells; one example of this differentiation is the acquisition of mature neuronal phenotypes [1]. For example, transient elevations ...
    • Peña Villalobos, Isaac; Piriz, Gabriela; Palma, Verónica; Sabat Kirkwood, Alejandro Pablo (Frontiers Media S.A., 2017)
      © 2017 Peña-Villalobos, Piriz, Palma and Sabat. Studies on the yolk and albumen content in bird eggs, and the effects of variations in their relative loads in the phenotype of the birds, have revealed multiple consequences ...
    • Sepulveda, Hugo; Aguilar, Rodrigo; Prieto, Catalina P.; Bustos, Francisco; Aedo Monsalve, Sócrates; Lattus Olmos, José; Van Zundert, Brigitte; Palma, Verónica; Montecino, Martín (Wiley, 2017)
      Wharton's Jelly mesenchymal stem cells (WJ-MSCs) are an attractive potential source of multipotent stem cells for bone tissue replacement therapies. However, the molecular mechanisms involved in their osteogenic conversion ...
    • Bergeron, Sadie A.; Milla, Luis A.; Villegas, Rosario; Shen, Meng Chieh; Burgess, Shawn M.; Allende Connelly, Miguel; Karlstrom, Rolf O.; Palma, Verónica (2008)
      The Hedgehog (Hh) signaling pathway plays critical instructional roles during embryonic development. Misregulation of Hh/Gli signaling is a major causative factor in human congenital disorders and in a variety of cancers. ...
    • Botelho, João Francisco; Smith Paredes, Daniel; Soto Acuña, Sergio; Núñez-León, Daniel; Palma, Verónica; Vargas, Alexander O. (John Wiley and Sons Inc., 2017)
      © 2016 Wiley Periodicals, Inc. In early theropod dinosaurs—the ancestors of birds—the hallux (digit 1) had an elevated position within the foot and had lost the proximal portion of its metatarsal. It no longer articulated ...
    • Bernal, Carolina; Araya, Claudia; Palma, Verónica; Bronfman, Miguel (Frontiers Research Foundation, 2015)
      © 2015 Bernal, Araya, Palma and Bronfman.The subventricular zone (SVZ) is one of the main niches of neural stem cells in the adult mammalian brain. Stem and precursor cells in this region are the source for neurogenesis ...
    • Rapacioli, Melina; Botelho, Joao; Cerda, Gustavo; Duarte, Santiago; Elliot, Matías; Palma, Verónica; Flores, Vladimir (2012)
      Background: Sonic hedgehog (Shh)/Gli pathway plays an important regulatory role on the neuroepithelial cells (NEc) proliferation in the dorsal regions of the developing vertebrate Central Nervous System. The aim of this ...
    • Milla, Luis A.; González-Ramírez, Claudia N.; Palma, Verónica (2012)
      The Sonic Hegdehog/GLI (SHH/GLI) pathway has been extensively studied for its role in developmental and cancer biology. During early embryonic development the SHH pathway is involved mainly in pattern formation, while in ...
    • Villanueva, Andrea A.; Puvogel, Sofía; Lois, Pablo; Muñoz-Palma, Ernesto; Ramírez Orellana, Manuel; Lubieniecki, Fabiana; Casco Claro, Fernando; Gallegos, Iván; García-Castro, Javier; Sanchez-Gomez, Pilar; Torres, Vicente A.; Palma, Verónica (Taylor and Francis Inc., 2018)
      © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group. Neuroblastoma (NB) is the most common pediatric extracranial solid tumor. It arises during development of the sympathetic nervous system. Netrin-4 (NTN4), ...
    • Villanueva, Andrea A.; Falcón, Paulina; Espinoza, Natalie; Solano, R. Luis; Milla, Luis A.; Hernandez-SanMiguel, Esther; Torres, Vicente A.; Sanchez-Gomez, Pilar; Palma, Verónica (Impact Journals LLC, 2017)
      Neogenin-1 (NEO1) is a transmembrane receptor involved in axonal guidance, angiogenesis, neuronal cell migration and cell death, during both embryonic development and adult homeostasis. It has been described as a dependence ...