Browsing by Author "dfadab4d-9a60-4010-9b31-77bf908535d4"

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    • Alterations in mouse liver monooxygenases by benzothiadiazoles 
      Pedemonte, Jaime; Olate, Juan; Cervantes, Paulina; Oberti, Carlos; Gil, Lionel (1981)
      Administration of 1,2,3-benzothiadiazoles to mice had a biphasic effect on liver microsomal monooxygenases. During the first 15 hr of treatment, an inhibition of the in vivo metabolism of hexobarbital, as well as of the ...
    • Differential stimulation of the GTPase activity of G-proteins by polylysine 
      Antonelli, Marcelo; Olate, Juan; Graf, Rolf; Allende, Catherine C.; Allende, Jorge E. (1992)
      Polylysine, polyornithine and, to a lesser extent, polyarginine were found to stimulate the GTPase activity of the purified recombinant α subunit of the human Gi-3 transducing protein αi-3. Optimal stimulation of 4- to ...
    • Inhibition by phenothiazine derivatives of the adenylate cyclase of amphibian oocytes 
      Olate, Juan; Jordana, Xavier; Allende, Catherine C.; Allende, Jorge E. (1983)
      The adenylate cyclase activity of membranes of Xenopus laevis oocytes and follicle cells was affected by the presence of 2-chloro-10-(3-aminopropyl)phenothiazine (CAPP) and two other antipsychotic drugs, fluphenazine and ...
    • Structure and function of G proteins 
      Olate, Juan; Allende, Jorge E. (1991)
      G proteins are heterotrimeric proteins involved in the transduction of a variety of external signals in all eukaryotic organisms. This review analyzes the molecular aspects of G protein structure and function. The cloning ...