Browsing by Author "e0144bab-fc9b-4f82-98ba-b76191c9c342"

Now showing items 1-4 of 4

    • Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons 
      Klein, Andres; Maldonado, Carola; Vargas, Lina M.; Gonzalez, Marcela; Robledo, Fermín; Perez de Arce, Karen; Muñoz, Francisco J.; Hetz Flores, Claudio; Alvarez, Alejandra R.; Zanlungo, Silvana (2011)
      Niemann-Pick type C (NPC) is a neurodegenerative disease characterized by the intralysosomal accumulation of cholesterol leading to neuronal apoptosis. We have previously reported the activation of the c-Abl/p73 proapoptotic ...
    • PC12 and neuro 2a cells have different susceptibilities to acetylcholinesterase-amyloid complexes, amyloid25-35 ... 
      Calderón, Frances H.; Bonnefont, Andrea; Muñoz, Francisco J.; Fernández, Virginia; Videla Cabrera, Luis; Inestrosa, Nibaldo C. (1999)
      This work addresses the differential effects of several oxidative insults on two neuronal cell lines, PC12 and Neuro 2a cells, extensively used as neuronal models in vitro. We measured cellular damage using the cytotoxic ...
    • Topology-driven nonlinear switching in Möbius discrete arrays 
      Muñoz, Francisco J.; Turitsyn, Sergei K.; Kivshar, Yuri S.; Molina Gálvez, Mario (American Physical Society, 2017)
      © 2017 American Physical Society.We examine the switching dynamics of discrete solitons propagating along two coupled discrete arrays which are twisted to form a Möbius strip. We analyze the potential of the topological ...
    • Vitamin E but not 17β-estradiol protects against vascular toxicity induced by β-amyloid wild type and the ... 
      Muñoz, Francisco J.; Opazo, Carlos; Gil-Gómez, Gabriel; Tapia, Gladys; Fernández, Virginia; Valverde, Miguel A.; Inestrosa, Nibaldo C. (2002)
      Amyloid β-peptide (Aβ) fibril deposition on cerebral vessels produces cerebral amyloid angiopathy that appears in the majority of Alzheimer's disease patients. An early onset of a cerebral amyloid angiopathy variant called ...