Browsing by Author "e6bc25d6-60a1-44cf-b924-4894a7b9de05"
Now showing items 1-12 of 12
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Garcia, G. G.; Miranda, H. F.; Noriega, V.; Sierralta, F.; Olavarría, L.; Zepeda, R. J.; Prieto, J. C. (2011)Atorvastatin is a statin that inhibits the 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase. Several landmark clinical trials have demonstrated the beneficial effects of statin therapy for primary and secondary ...
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Miranda, H. F.; Pinardi, G. (Elsevier Inc., 1998)The mechanism of action of tramadol includes the activation of opioid receptors, and the potential ability of the drug to induce tolerance and physical dependence has been evaluated in different animal species and humans. ...
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Miranda, H. F.; Sierralta, F.; Jorquera, V.; Poblete, P.; Prieto, J. C.; Noriega, V. (Birkhauser Verlag AG, 2017)© 2017, Springer International Publishing. Objective: Diabetic neuropathy (DN) is the most common complication of diabetes and pain is one of the main symptoms of diabetic neuropathy, however, currently available drugs are ...
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Pinardi, G.; Pelissier Serrano, Teresa; Kramer, V.; Paeile, C.; Miranda, H. F. (1994)1. The effects of an infusion of cytidine-5′-diphosphocholine (CDP-choline) on the relaxation induced by exogenous acetylcholine (ACh) was studied in the isolated and perfuded external (ECB) and internal (ICB) carotid ...
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Miranda, H. F.; Puig, M. M.; Romero, M. A.; Prieto, J. C. (2009)The purpose of the present study was to evaluate the nature of the antinociceptive interaction among dexketoprofen (DEX), a mixed inhibitor of the cyclo-oxygenases, and tramadol (TRAM), a weak opioid with monoaminergic ...
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Cerda, S.; Miranda, H. F.; Pinardi, G. (1993)
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Sierralta, F.; Miranda, H. F.; Pinardi, G.; Mendez, M. (Springer-Verlag, 1995)The antinociceptive activity of antidepressant drugs is poorly understood. In this study, using the acetic acid writhing test in mice, the antinociception produced by clomipramine (CLO), maprotiline (MAP), imipramine (IMI), ...
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Miranda, H. F.; Poblete, P.; Sierralta, F.; Noriega, V.; Prieto, J. C.; Zepeda, R. J. (Birkhauser Verlag AG, 2019)Neuropathic pain is a complication of cancer and diabetes mellitus and the most commonly used drugs in the treatment of the diabetic neuropathic pain have only limited efficacy. The aim of this study was to evaluate the ...
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Miranda, H. F.; Silva, W. I.; Wolstenholme, W. W.; Cuevas, N.; Ucros, A.; Bustamante, D.; Fernández, E. H. (1991)SP produces two different muscular responses in the isolated vas deferens of the rat. 1) A myotropic, post-synaptic effect that results from stimulation of one subtype of SP receptor, located on the membrane of the smooth ...
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Muñoz, J.; Navarro, C.; Noriega, V.; Pinardi,; Sierralta, F.; Prieto, J. C.; Miranda, H. F. (2010)Objective and design: The antinociception induced by the intraperitoneal coadministration in mice of combinations of metamizol and paracetamol was evaluated in the tail flick test and orofacial formalin test. Methods: The ...
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Miranda, H. F.; Sierralta, F.; Prieto, J. C. (2009)Opioids and non-steroidal anti-inflammatory drugs (NSAIDs) are used to relieve acute and chronic pain. The purpose of this study was to determine the degree of interaction between dexketoprofen and NSAID examples of COXs ...
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Miranda, H. F.; Silva, E.; Pinardi, (2004)The intraperitoneal administration of morphine, diclofenac, ketoprofen, meloxicam, metamizol, paracetamol and piroxicam induced dose-dependent antinociception in mice tested with the acetic acid writhing test. The ...