Browsing by Author "e7b6c672-b3bd-4a87-a8fb-dbeb84d911fb"

Now showing items 1-5 of 5

    • Hyperosmotic stress stimulates autophagy via polycystin-2 
      Peña Oyarzún, Daniel; Troncoso Cotal, Rodrigo; Kretschmar, Catalina; Hernando, Cecilia; Budini, Mauricio; Morselli, Eugenia; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Impact Journals, 2017)
      Various intracellular mechanisms are activated in response to stress, leading to adaptation or death. Autophagy, an intracellular process that promotes lysosomal degradation of proteins, is an adaptive response to several ...
    • PKD2/polycystin-2 induces autophagy by forming a complex with BECN1 
      Peña Oyarzún, Daniel; Rodríguez Peña, Marcelo; Burgos Bravo, Francesca; Vergara, Ángelo; Kretschmar Montecinos, Catalina; Sotomayor Flores, Cristián; Ramírez Sarmiento, César A.; De Smedt, Humbert; Reyes Rojas, Montserrat; Pérez, William; Torres Gómez, Vicente; Morselli, Eugenia; Altamirano, Francisco; Wilson, Christian; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Taylor & Francis, 2020)
      Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a ...
    • Polycystin-2 is required for starvation- And rapamycin-induced atrophy in myotubes 
      Kretschmar, Catalina; Peña Oyarzún, Daniel; Hernando, Cecilia; Hernández Moya, Nadia; Molina Berríos, Alfredo Enrique; Hernández-Cáceres, María Paz; Lavandero González, Sergio; Budini, Mauricio; Morselli, Eugenia; Parra, Valentina; Troncoso, Rodrigo; Criollo Céspedes, Alfredo (Frontiers Media S.A., 2019)
      Copyright © 2019 Kretschmar, Peña-Oyarzun, Hernando, Hernández-Moya, Molina-Berríos, Hernández-Cáceres, Lavandero, Budini, Morselli, Parra, Troncoso and Criollo.Muscle atrophy involves a massive catabolism of intracellular ...
    • Role of Autophagy in the Microenvironment of Oral Squamous Cell Carcinoma 
      Peña Oyarzún, Daniel; Reyes Rojas, Montserrat; Hernández Cáceres, María Paz; Kretschmar, Catalina; Morselli, Eugenia; Ramírez Sarmiento, César; Lavandero González, Sergio; Torres Gómez, Vicente; Criollo, Alfredo (Frontiers Media, 2020)
      Oral squamous cell carcinoma, the most common type of oral cancer, affects more than 275,000 people per year worldwide. Oral squamous cell carcinoma is very aggressive, as most patients die after 3 to 5 years post-diagnosis. ...
    • Wnt/beta-Catenin Signaling in Oral Carcinogenesis 
      Reyes Rojas, Montserrat; Flores Lillo, Tania; Betancur, Diego; Peña Oyarzún, Daniel; Torres Gómez, Vicente (MDPI, 2020)
      Oral carcinogenesis is a complex and multifactorial process that involves cumulative genetic and molecular alterations, leading to uncontrolled cell proliferation, impaired DNA repair and defective cell death. At the ...