Browsing by Author "e8361e95-a458-4e40-a34a-9065637b8eeb"

Now showing items 1-5 of 5

    • alpha (V) beta (3) Integrin regulates astrocyte reactivity 
      Lagos Cabre, Raúl; Álvarez, Álvaro; Kong, Milene; Burgos Bravo, Francesca; Cárdenas, Areli; Rojas Mancilla, Edgardo; Pérez Núñez, Ramón Daniel; Herrera Molina, Rodrigo; Rojas, Fabiola; Schneider, Pascal; Herrera-Marschitz Muller, Mario; Quest, Andrew F. G.; van Zundert, Brigitte; Leyton Campos, Lisette (BIOMED Central Ltd., 2017)
      Background: Neuroinflammation involves cytokine release, astrocyte reactivity and migration. Neuronal Thy-1 promotes DITNC1 astrocyte migration by engaging alpha(V)beta(3) Integrin and Syndecan-4. Primary astrocytes express ...
    • Application of force to a syndecan-4 containing complex with thy-1 alpha (v) beta (3) integrin accelerates ... 
      Burgos Bravo, Francesca; Martínez Meza, Samuel; Quest, Andrew F. G.; Wilson Moya, Christian; Leyton Campos, Lisette (Frontiers Media, 2020)
      Inflammation contributes to the genesis and progression of chronic diseases, such as cancer and neurodegeneration. Upregulation of integrins in astrocytes during inflammation induces neurite retraction by binding to the ...
    • Connexins in Astrocyte Migration 
      Lagos Cabré, Raúl; Burgos Bravo, Francesca; Ávalos, Ana María; Leyton, Lisette (Frontiers Media, 2020)
      Astrocytes have long been considered the supportive cells of the central nervous system, but during the last decades, they have gained much more attention because of their active participation in the modulation of neuronal ...
    • Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration 
      Álvarez, Álvaro; Lagos Cabré, Raúl; Kong, Milene; Cárdenas, Areli; Burgos Bravo, Francesca; Schneider, Pascal; Quest, Andrew F. G.; Leyton Campos, Lisette (Elsevier, 2016)
      Our previous reports indicate that ligand-induced alpha(v)beta(3) integrin and Syndecan-4 engagement increases focal adhesion formation and migration of astrocytes. Additionally, ligated integrins trigger ATP release through ...
    • PKD2/polycystin-2 induces autophagy by forming a complex with BECN1 
      Peña Oyarzún, Daniel; Rodríguez Peña, Marcelo; Burgos Bravo, Francesca; Vergara, Ángelo; Kretschmar Montecinos, Catalina; Sotomayor Flores, Cristián; Ramírez Sarmiento, César A.; De Smedt, Humbert; Reyes Rojas, Montserrat; Pérez, William; Torres Gómez, Vicente; Morselli, Eugenia; Altamirano, Francisco; Wilson, Christian; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Taylor & Francis, 2020)
      Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a ...