Browsing by Author "e88b2c44-614b-4b5d-81a9-55f02696cc29"

Now showing items 1-8 of 8

    • Antinociception and anti-inflammation induced by simvastatin in algesiometric assays in mice 
      Miranda, Hugo F.; Noriega, Viviana; Olavarria, Loreto; Zepeda, Ramiro J.; Sierralta, Fernando; Prieto, Juan C. (2011)
      Statins, belonging to a well-known drug class used for lowering cholesterol through competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, also have other pleiotropic properties, such as ...
    • Antinociception induced by rosuvastatin in murine neuropathic pain 
      Miranda, Hugo F.; Sierralta, Fernando; Aranda, Nicolas; Poblete, Paula; Castillo, Rodrigo; Noriega, Viviana; Prieto, Juan (Elsevier, 2018-06)
      Background: Neuropathic pain, and subsequent hypernociception, can be induced in mice by paclitaxel (PTX) administration and partial sciatic nerve ligation (PSNL). Its pharmacotherapy has been a clinical challenge, due to ...
    • Antinociceptive Interaction of Tramadol with Gabapentin in Experimental Mononeuropathic Pain 
      Miranda, Hugo F.; Noriega, Viviana; Prieto, Juan Carlos; Zanetta, Pilar; Castillo, Rodrigo; Aranda, Nicol as; Sierralta, Fernando (Nordic Association for the Publication of BCPT, 2016)
      Neuropathic pain is the result of injury to the nervous system, and different animal models have been established to meet the manifestations of neuropathy. The pharmacotherapy for neuropathic pain includes gabapentin and ...
    • Neostigmine interactions with non steroidal anti-inflammatory drugs 
      Miranda, Hugo F.; Sierralta, Fernando; Pinardi, Gianni (2002)
      1. The common mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs) is the inhibition of the enzyme cyclo-oxygenase (COX), however, this inhibition is not enough to completely account for the efficacy of ...
    • Pharmacological interaction between NSAIDS with clomipramine and risperidone in mice visceral pain 
      Vargas, Claudio Gonzalez; Miranda, Hugo F.; Sierralta, Fernando; Noriega, Viviana; Prieto, Juan Carlos (Wiley-Liss Inc., 2019)
      Nonsteroidal anti-inflammatory drugs (NSAIDs) possess as primary action mechanism the inhibition of cyclooxygenases (COX-1, COX-2, and COX-3), thus producing a decreasing prostaglandin synthesis. This study was designed ...
    • Synergism between fentanyl and tramadol in tonic inflammatory pain: The orofacial formalin test 
      Miranda, Hugo F.; Noriega, Viviana; Zepeda, Ramiro J.; Sierralta, Fernando; Prieto, Juan C. (2012)
      Opioids have been used for long time to management of pain, the coadministration of two opioids may induce synergism. The present study was conducted to determine the antinociceptive interaction between the dual mechanism ...
    • Synergism between gabapentin–tramadol in experimental diabetic neuropathic pain 
      Miranda, Hugo F.; Sierralta, Fernando; Aranda, Nicolas; Astaburuaga Poblete, Paula; Noriega, Viviana; Prieto, Juan C. (Blackwell Publishing Ltd, 2018)
      © 2018 Société Française de Pharmacologie et de Thérapeutique Neuropathic pain is associated with several conditions such as surgery, cancer, and diabetes and can be induced experimentally. Among the drugs used as monotherapy ...
    • Systemic synergism between codeine and morphine in three pain models in mice 
      Miranda, Hugo F.; Noriega, Viviana; Zepeda, Ramiro J.; Sierralta, Fernando; Prieto, Juan C. (Elsevier B.V., 2013)
      Background: The combination of two analgesic agents offers advantages in pain treatment. Codeine and morphine analgesia is due to activation of opioid receptor subtypes. Methods: This study, performed in mice using ...