Browsing by Author "eb2f333b-fa69-4325-b042-fa6405309063"
Now showing items 1-7 of 7
-
Vargas, Romina; Riquelme, Bárbara; Fernández, Javier; Álvarez, Daniela; Pérez, Ignacio F.; Cornejo, Pamela; Fernández, Virginia; Videla Cabrera, Luis (Blackwell Publishing Inc., 2019)© 2018 International Union of Biochemistry and Molecular Biology Docosahexaenoic acid (DHA) and 3,3′,5-triiodothyronine (T 3 ) combined protocol affords protection against liver injury via AMPK signaling supporting energy ...
-
Fernández Arancibia, Virginia; Cornejo, Pamela; Tapia Opazo, Gladys; Videla Cabrera, Luis (Academic Press Inc., 1997)Hyperthyroidism enhances the prooxidant activity of the liver by elevating superoxide radical and/or hydrogen peroxide generation in microsomal, mitochondrial, and peroxisomal fractions, with an increased respiratory burst ...
-
Cornejo, Pamela; Tapia Opazo, Gladys; Puntarulo, Susana; Galleano, Mónica; Videla Cabrera, Luis; Fernández Arancibia, Virginia (2001)The involvement of cytosolic nitric oxide (NO) and mitochondrial superoxide radical (O2 ·-) production was evaluated as a mechanism triggering liver oxidative stress in lindane (40 mg/kg) or L-3,3′,5-triiodothyronine (T3, ...
-
Videla Cabrera, Luis; Fernández Arancibia, Virginia; Cornejo, Pamela; Vargas, Romina (2012)The liver is a major organ responsible for most functions of cellular metabolism and a mediator between dietary and endogenous sources of energy for extrahepatic tissues. In this context, adenosine-monophosphate- (AMP-) ...
-
Romanque, Pamela; Cornejo, Pamela; Valdés, Solange; Videla Cabrera, Luis (2011)Background: Oxidative stress associated with 3,3′,5-triiodo-l- thyronine (T3)-induced calorigenesis upregulates the hepatic expression of mediators of cytoprotective mechanisms. The aim of this study was to evaluate the ...
-
Videla Cabrera, Luis; Cornejo, Pamela; Romanque, Pamela; Santibáñez, Catherine; Castillo, Iván; Vargas, Romina (2012)L-3,3′,5-triiodothyronine (T3) administration upregulates nuclear factor-E2-related factor 2 (Nrf2) in rat liver, which is redox-sensitive transcription factor mediating cytoprotection. In this work, we studied the role ...
-
Fernández, Virginia; Tapia, Gladys; Varela, Patricia; Cornejo, Pamela; Videla Cabrera, Luis (2009)3,3,5-L-Triiodothyronine (T 3) exerts significant protection against ischemia-reperfusion (IR) liver injury in rats. Considering that the underlying mechanisms are unknown, the aim of this study was to assess the involvement ...