Browsing by Author "ecc52cc2-f4b9-46a6-9a8c-3493bae10f3f"

Now showing items 1-7 of 7

    • Antiviral activity of phosphonoformate on rotavirus transcription and replication 
      Ríos, Maritza; Muñoz, Marianne; Spencer, Eugenio (1995)
      The antiviral effect of foscarnet (PFA) on the replication of rotavirus, a member of the Reoviridae, was studied. The pyrophosphate analogue is an effective inhibitor of several viral polymerases acting on the enzyme ...
    • Characteristics and analysis of electropherotypes of human rotavirus isolated in Chile 
      Spencer, Eugenio; Avendaño, Fidel; Araya, Magdalena (1983)
      Electropherotypes of human rotavirus from stool samples of hospitalized and ambulatory infants with acute diarrhea were analysed. Thirty-two different electropherotypes were observed in 142 cases in which the viral genome ...
    • Chitosan-based delivery of avian reovirus fusogenic protein p10 gene: in vitro and in vivo studies towards ... 
      Robles Planells, Claudia; Barrera Ávalos, Carlos; Rojo, Leonel E.; Spencer, Eugenio; Cortez San Martín, Eugenio; Matiacevich, Silvia; Pavez, Jorge; Milla, Luis A.; Navarro, Franco D.; Martínez, Brandon A; Bravo, Francisco J.; Mella, Andrea; Huidobro Toro, Juan Pablo; Fernández, Ricardo; Escobar Álvarez, Alejandro; Acuña Castillo, Claudio (Hindawi, 2020)
      Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus-mediated impact on tumor growth depends on the activation of specific antitumor immune ...
    • Chitosan-based nanoparticles for Intracellular delivery of ISAV fusion protein cDNA into melanoma cells: a ... 
      Robles Planells, Claudia; Sánchez-Guerrero, Giselle; Barrera Ávalos, Carlos; Matiacevich, Silvia; Rojo, Leonel E.; Pavéz, Jorge; Salas Huenuleo, Edison; Kogan, Marcelo J.; Escobar Álvarez, Alejandro; Milla, Luis A.; Fernández, Ricardo; Imarai, Mónica; Spencer, Eugenio; Huidobro Toro, Juan Pablo; Acuña Castillo, Claudio (Hindawi, 2020)
      Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein-mediated syncytium formation ...
    • Effect of interferon and 2′,5′-oligoadenylates on rotavirus RNA synthesis 
      Ríos, Maritza; Muñoz, Marianne; Torrence, Paul F.; Spencer, Eugenio (1995)
      Based on the antiviral effect of interferon on rotavirus replication the inhibitory effect of 2′,5′-oligoadenylates on MRNA and double-stranded RNA synthesis was studied using an in vitro assay. The chemically synthesized ...
    • Effect of yeast (Xanthophyllomyces dendrorhous) and plant (Saint John's wort, lemon balm, and rosemary) ... 
      Reyes Cerpa, Sebastián; Vallejos Vidal, Eva; González Bown, María José; Morales Reyes, Jonathan; Pérez Stuardo, Diego; Vargas, Deborah; Imarai, Mónica; Cifuentes Guzmán, Víctor; Spencer, Eugenio; Sandino, Ana María; Reyes López, Felipe E. (Elsevier, 2018)
      Salmon farming may face stress due to the intensive culture conditions with negative impacts on overall performance. In this aspect, functional feed improves not only the basic nutritional requirements but also the health ...
    • Respiratory syncytial virus detection by dot blot hybridization with a nonradioactive synthetic oligo ... 
      Hernández, Oscar; Fernandez, Jorge; Valenzuela, Sofia; Sandino, Ana Maria; Pizarro, Jaqueline; Vasquez, Monica; Yudelevich, Arturo; Spencer, Eugenio (1992)
      A synthetic oligodeoxynucleotide corresponding to a region of the nucleocapside gene (N) of respiratory syncytial virus (RSV), was used as a DNA probe to develop a nonradioactive hybridization assay for the detection of ...