Browsing by Author "ee4f7244-6911-4c7f-8270-43a64cc24288"
Now showing items 1-11 of 11
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ACh and ATP mediate excitatory transmission in cat carotid identified chemoreceptor units in vitro Varas, Rodrigo; Alcayaga Urbina, Julio; Iturriaga, Rodrigo (Elsevier, 2003)Several molecules have been proposed as excitatory transmitters between glomus (type 1) cells and nerve terminals of petrosal ganglion (PG) neurons in the carotid body (CB). We tested whether ACh and ATP have a role to ...
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Andrade, David C.; Iturriaga, Rodrigo; Jeton, Florine; Alcayaga Urbina, Julio; Voituron, Nicolas; Del Rio, Rodrigo (Springer New York LLC, 2018)© 2018, Springer International Publishing AG, part of Springer Nature. The carotid body (CB) chemoreceptors sense changes in arterial blood gases. Upon stimulation CB chemoreceptors cells release one or more transmitters ...
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Iturriaga, Rodrigo; Cerpa, Verónica; Zapata, Patricio; Alcayaga Urbina, Julio (Elsevier, 2003)The petrosal ganglion (PG) is entirely constituted by the perikarya of primary sensory neurons, part of which innervates the carotid body via the carotid sinus nerve (CSN). Application of acetylcholine (ACh) or nicotine ...
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Alcayaga Urbina, Julio; Varas, Rodrigo; Arroyo, Jorge; Iturriaga, Rodrigo; Zapata, Patricio (1999)We have recently reported that application of acetylcholine (ACh) or nicotine to the petrosal ganglion - the sensory ganglion of the glossopharyngeal nerve - elicits a burst of discharges in the carotid nerve branch, ...
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Iturriaga, Rodrigo; Alcayaga Urbina, Julio (2007)Exposure to chronic intermittent hypoxia (CIH) for 4 days enhances the cat carotid body (CB) chemosensory responses to acute hypoxia. However, it is not known if CIH enhances the responses of the petrosal ganglion (PG) ...
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Moya, Esteban A.; Alcayaga Urbina, Julio; Iturriaga, Rodrigo (Elsevier, 2012)Nitric oxide (NO), at physiological concentrations, is a tonic inhibitory modulator of carotid body (CB) chemosensory discharges. NO modulates the chemoreception process by several mechanisms, indirectly by modifying the ...
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Alcayaga Urbina, Julio; Varas, Rodrigo; Arroyo, Jorge; Iturriaga, Rodrigo; Zapata, Patricio (Elsevier, 1999)NaCN is a classical stimulus used to elicit discharges from carotid body chemoreceptors. The effect is assumed to be mediated by glomus (type I) cells, which release an excitatory transmitter for the excitation of carotid ...
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Alcayaga Urbina, Julio; Iturriaga, Rodrigo; Varas, Rodrigo; Arroyo, Jorge; Zapata, Patricio (1998)The petrosal ganglion innervates carotid body chemoreceptors through the carotid (sinus) nerve. These primary sensory neurons are activated by transmitters released from receptor (glomus) cells, acetylcholine (ACh) having ...
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Iturriaga, Rodrigo; Alcayaga Urbina, Julio; Rey, Sergio (1998)We studied the effects of the nitric oxide (NO) synthase inhibitor, Nω- nitro-L-arginine methyl ester (L-NAME), and the NO donor, sodium nitroprusside (SNP) on cat chemosensory responses to intravenous injections of NaCN ...
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Stim-activated TRPC-ORAI channels in pulmonary hypertension induced by chronic intermittent hypoxia Castillo Galán, Sebastián; Arenas, Germán A.; Reyes, Roberto V.; Krause, Bernardo J.; Iturriaga, Rodrigo (SAGE, 2020)Obstructive sleep apnea (OSA), a breathing disorder featured by chronic intermittent hypoxia (CIH) is associated with pulmonary hypertension (PH). Rodents exposed to CIH develop pulmonary vascular remodeling and PH, but ...
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Andrade, David C.; Iturriaga, Rodrigo; Toledo, Camilo; Lucero, Claudia M.; Díaz, Hugo S.; Arce-Álvarez, Alexis; Retamal, Mauricio A.; Marcus, Noah J.; Alcayaga Urbina, Julio; Del Rio, Rodrigo (Springer New York LLC, 2018)© 2018, Springer International Publishing AG, part of Springer Nature. The carotid body (CB) is the main arterial chemoreceptor involved in oxygen sensing. Upon hypoxic stimulation, CB chemoreceptor cells release ...