Browsing by Author "ef3e358d-ec3f-4d5a-ab23-be76a26244ab"
Now showing items 1-5 of 5
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Cipriani, Micaella; Toloza, Jeannette; Bradford, Lara; Putzu, Eugenia; Vieites, Marisol; Curbelo, Estela; Tomaz, Ana; Garat, Beatriz; Guerrero, Juan; Gancheff, Jorge; Maya Arango, Juan; Olea Azar, Claudio; Gambino, Dinorah; Otero, Lucía (Wiley-VCH Verlag, 2014)Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, is a major health problem worldwide. In this work, we report the development of palladium and platinum metal complexes with 5-nitrofuryl-containing ...
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Micaella, Cipriani; Rostan, Santiago; León, Ignacio; Li, Zhu-Hong; Gancheff, Jorge; Kemmerling Weis, Ulrike; Olea Azar, Claudio; Etcheverry, Susana; Docampo, Roberto; Gambino, Dinorah; Otero, Lucía (Springer, 2020)Bisphosphonates are the most commonly prescribed drugs for the treatment of osteoporosis and other bone illnesses. Some of them have also shown antiparasitic activity. In search of improving the pharmacological profile of ...
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Rodríguez Arce, Esteban; Putzu, Eugenia; Lapier, Michel; Maya Arango, Juan; Olea Azar, Claudio; Echeverría, Gustavo A.; Piro, Oscar E.; Medeiros, Andrea; Sardi, Florencia; Comini, Marcelo; Risi, Gastón; Salinas, Gustavo; Correia, Isabel; Pessoa, João Costa; Otero, Lucía (Royal Society of Chemistry, 2019)In the search for a more effective chemotherapy for the treatment of Chagas' disease and human African trypanosomiasis, caused by Trypanosoma cruzi and Trypanosoma brucei parasites, respectively, the use of organometallic ...
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Vieites, Marisol; Otero, Lucía; Santos, Diego; Olea Azar, Claudio; Norambuena, Ester; Aguirre, Gabriela; Cerecetto, Hugo; González, Mercedes; Kemmerling Weis, Ulrike; Morello Casté, Antonio; Maya Arango, Juan; Gambino, Dinorah (2009)Eight new platinum(II) complexes with 3-(5-nitrofuryl)acroleine thiosemicarbazones showing anti-trypanosomal activity were synthesized, characterized and in vitro evaluated. Most of the complexes showed IC50 values in the ...
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Rodríguez Arce, Esteban; Machado, Ignacio; Rodríguez, Belén; Lapier, Michel; Zúñiga, María Carolina; Maya Arango, Juan; Olea Azar, Claudio; Otero, Lucía; Gambino, Dinorah (Elsevier Inc., 2017)© 2017 Elsevier Inc. American Trypanosomiasis is a chronic infection discovered and described in 1909 by the Brazilian scientist Carlos Chagas. It is caused by the protozoan parasite Trypanosoma cruzi. Although it affects ...