Browsing by Author "ef400d6c-2dda-40e0-b390-47c062794305"

Now showing items 1-5 of 5

    • A BK (Slo1) channel journey from molecule to physiology 
      Contreras, Gustavo F.; Castillo, Karen; Enrique, Nicolás; Carrasquel Ursulaez, Willy; Castillo, Juan Pablo; Milesi, Verónica; Neely, Alan; Alvarez, Osvaldo; Ferreira, Gonzalo; Gonzalez, Carlos; Latorre, Ramón (Taylor and Francis Inc., 2013)
      Calcium and voltage-activated potassium (BK) channels are key actors in cell physiology, both in neuronal and non-neuronal cells and tissues. Through negative feedback between intracellular Ca2+ and membrane voltage, BK ...
    • Gating charge displacement in a monomeric voltage-gated proton (Hv1) channel 
      Carmona, Emerson M.; Peter Larsson, H.; Neely, Alan; Alvarez, Osvaldo; Latorre, Ramón; Gonzalez, Carlos (National Academy of Sciences, 2018)
      © 2018 National Academy of Sciences. All Rights Reserved. The voltage-gated proton (Hv1) channel, a voltage sensor and a conductive pore contained in one structural module, plays important roles in many physiological ...
    • Hyperkalemic periodic paralysis M1592V mutation modifies activation in human skeletal muscle Na+ channel 
      Rojas, Cecilia V.; Neely, Alan; Velasco-Loyden, Gabriela; Palma, Veronica; Kukuljan Padilla, Manuel (1999)
      Mutations in the human skeletal muscle Na+ channel underlie the autosomal dominant disease hyperkalemic periodic paralysis (HPP). Muscle fibers from affected individuals exhibit sustained Na+ currents thought to depolarize ...
    • Modulation of BK channel voltage gating by different auxiliary β subunits 
      Contreras, Gustavo F.; Neely, Alan; Alvarez, Osvaldo; Gonzalez, Carlos; Latorre, Ramón (2012)
      Calcium- and voltage-activated potassium channels (BK) are regulated by a multiplicity of signals. The prevailing view is that different BK gating mechanisms converge to determine channel opening and that these gating ...
    • Properties of the voltage-gated proton channel gating currents 
      Carmona, Emerson M.; Baez Nieto, David; Pupo, Amaury; Castillo, Karen; Álvarez Araya, Osvaldo; Neely, Alan; Latorre, Ramón; González, Carlos (Cell Press, 2018)