Browsing by Author "f41a9c65-a52b-4143-9a46-272289db3ea6"

Now showing items 1-6 of 6

    • Chaski, a novel drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional ... 
      Delgado, María Graciela; Oliva, Carlos; López, Estefanía; Ibacache, Andrés; Galaz, Alex; Delgado, Ricardo; Barros, L. Felipe; Sierralta, Jimena (Nature Publishing Group, 2018)
      The intercellular transport of lactate is crucial for the astrocyte-to-neuron lactate shuttle (ANLS), a model of brain energetics according to which neurons are fueled by astrocytic lactate. In this study we show that the ...
    • Hindsight regulates photoreceptor axon targeting through transcriptional control of jitterbug/Filamin and ... 
      Oliva, Carlos; Molina-Fernandez, Claudia; Maureira, Miguel; Candia, Noemi; López, Estefanía; Hassan, Bassem; Aerts, Stein; Cánovas, José; Olguín, Patricio; Sierralta, Jimena (John Wiley and Sons Inc., 2015)
      © 2015 Wiley Periodicals, Inc.During axon targeting, a stereotyped pattern of connectivity is achieved by the integration of intrinsic genetic programs and the response to extrinsic long and short-range directional cues. ...
    • Regulation of axonal development by the nuclear protein hindsight (pebbled) in the Drosophila visual system 
      Oliva, Carlos; Sierralta, Jimena (Academic Press Inc., 2010)
      The molecules and networks involved in the process of acquisition and maintenance of the form of a mature neuron are not completely known. Using a misexpression screen we identified the gene hindsight as a gene involved ...
    • Regulation of Drosophila Brain Wiring by Neuropil Interactions via a Slit-Robo-RPTP Signaling Complex 
      Oliva, Carlos; Soldano, Alessia; Mora, Natalia; De Geest, Natalie; Claeys, Annelies; Erfurth, Maria-Luise; Sierralta, Jimena; Ramaekers, Ariane; Dascenco, Dan; Ejsmont, Radoslaw K.; Schmucker, Dietmar; Sánchez Soriano, Natalia; Hassan, Bassem A. (Cell Press, 2016)
      The axonal wiring molecule Slit and its Round-About (Robo) receptors are conserved regulators of nerve cord patterning. Robo receptors also contribute to wiring brain circuits. Whether molecular mechanisms regulating these ...
    • Slit neuronal secretion coordinates optic lobe morphogenesis in Drosophila 
      Caipo Coral, Lorena; González Ramírez, M. Constanza; Guzmán Palma, Pablo; Contreras, Esteban; Palominos, Tomás; Fuenzalida Uribe, Nicolás; Hassan, Bassem A.; Campusano, Jorge M.; Sierralta, Jimena; Oliva, Carlos (Elsevier, 2020)
      The complexity of the nervous system requires the coordination of multiple cellular processes during development. Among them, we find boundary formation, axon guidance, cell migration and cell segregation. Understanding ...
    • The transcription factor SoxD controls neuronal guidance in the Drosophila visual system 
      Contreras, Esteban G.; Palominos, Tomás; Glavic Maurer, Álvaro; Brand, Andrea H.; Sierralta, Jimena; Oliva, Carlos (Nature Publishing Group, 2018)
      © 2018, The Author(s). Precise control of neurite guidance during development is essential to ensure proper formation of neuronal networks and correct function of the central nervous system (CNS). How neuronal projections ...