Browsing by Author "f7790ee7-7327-4c1f-89c0-6cd1f03f3565"

Now showing items 1-3 of 3

    • Galectin-8 as an immunosuppressor in experimental autoimmune encephalomyelitis and a target of human early ... 
      Pardo, Evelyn; Carcamo, Claudia; Uribe San Martin, Reinaldo; Ciampi, Ethel; Segovia Miranda, Fabián; Curkovic Peña, Cristobal; Montecino, Fabián; Holmes, Christopher; Tichauer, Juan E.; Acuña, Eric; Osorio Barrios, Francisco; Castro, Marjorie; Cortes, Priscilla; Oyanadel, Claudia; Valenzuela, David M.; Pacheco, Rodrigo; Naves Pichuante, Rodrigo Antonio; Soza, Andrea; González, Alfonso (Public Library Science, 2017)
      Galectin-8 (Gal-8) is a member of a glycan-binding protein family that regulates the immune system, among other functions, and is a target of antibodies in autoimmune disorders. However, its role in multiple sclerosis (MS), ...
    • Identification of novel 11β-HSD1 inhibitors by combined ligand- and structure-based virtual screening 
      Lagos, Carlos F.; Vecchiola, Andrea; Allende, Fidel; Fuentes, Cristobal A.; Tichauer, Juan E.; Valdivia, Carolina; Solari, Sandra; Campino, Carmen; Tapia-Castillo, Alejandra; Baudrand, Rene; Villarroel, Pia; Cifuentes, Mariana; Owen, Gareth I.; Carvajal, Cristian A. (2014)
      11 beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts cortisone to cortisol in a NADPH dependent manner. Overexpression of 11β-HSD1 in key metabolic tissues is related to the development of type 2 diabetes, ...
    • Protective role of interferon-gamma during the chronic phase of experimental autoimmune encephalomyelitis 
      Arellano, G.; Tichauer, Juan E.; Acuña, E.; Castillo, C.; Naves Pichuante, Rodrigo Antonio (2016)