Browsing by Author "fc2d4b5c-e0a7-4cfa-bd46-1c9fac9cf46a"

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    • Caspase 8 inhibition increases the infection with trypanosoma cruzi in thehuman trophoblast cell line (bewo) 
      Carrillo, Ileana; Castillo, Christian; Droguett, Daniel; Muñoz, Lorena; Liempi, Ana; Maya Arango, Juan; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (2016)
      Congenital Chagas’ disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi), which is able to cross the placental barrier and infect both the placenta and fetus. However, congenital transmission ...
    • Comparative ex vivo infection with Trypanosoma cruzi and Toxoplasma gondii of human, canine and ovine ... 
      Liempi, Ana; Castillo Rivas, Christian; Medina, Lisvaneth; Galanti, Norbel; Maya Arango, Juan; Parraguez Gamboa, Víctor; Kemmerling Weis, Ulrike (Elsevier, 2020)
      Trypanosoma cruzi, the causative agent of Chagas disease, and Toxoplasma gondii, which is responsible for Toxoplasmosis, are two parasites that cause significant protozoan zoonoses and consequently important economic losses ...
    • Differential infectivity of two Trypanosoma cruzi strains in placental cells and tissue 
      Medina, Lisvaneth; Castillo, Christian; Liempi, Ana; Herbach, Mathias; Cabrera, Gonzalo; Valenzuela, Lucía; Galanti Garrone, Norbel; de los Angeles Curto, María; Schijman, Alejandro G.; Kemmerling Weis, Ulrike (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. Congenital Chagas disease, caused by Trypanosoma cruzi (T. cruzi), has become epidemiologically relevant. The probability of congenital transmission depends on the maternal and developing fetal/newborn ...
    • Erratum for González-Herrera et al., “Simvastatin Attenuates Endothelial Activation through 15-Epi-Lipoxin ... 
      González Herrera, Fabiola; Cramer, Allysson; Pimentel, Pollyana; Castillo, Christian; Liempi, Ana; Kemmerling Weis, Ulrike; Machado, Fabiana S.; Maya Arango, Juan (American Society Microbiology, 2017)
    • Old yellow enzyme from Trypanosoma cruzi exhibits in vivo prostaglandin F-2 alpha synthase activity and has ... 
      Díaz Viraque, Florencia; Chiribao, María Laura; Trochine, Andrea; González Herrera, Fabiola; Castillo, Christian; Liempi, Ana; Kemmerling Weis, Ulrike; Diego Maya, Juan; Robello, Carlos (Frontiers media SA, 2018)
      The discovery that trypanosomatids, unicellular organisms of the order Kinetoplastida, are capable of synthesizing prostaglandins raised questions about the role of these molecules during parasitic infections. Multiple ...
    • Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role ... 
      Campos Estrada, Carolina; Liempi, Ana; González Herrera, Fabiola; Lapier, Michel; Kemmerling Weis, Ulrike; Pesce Reyes, Bárbara; Ferreira, Jorge; López Muñoz, Rodrigo; Maya Arango, Juan (Public Library of Science, 2015)
      © 2015 Campos-Estrada et al.Trypanosoma cruzi is the causal agent of Chagas Disease that is endemic in Latin American, afflicting more than ten million people approximately. This disease has two phases, acute and chronic. ...
    • Simvastatin attenuates endothelial activation through 15-epi-lipoxin A4 production in murine chronic Chagas ... 
      González Herrera, Fabiola; Cramer, Allysson; Pimentel, Pollyana; Castillo, Christian; Liempi, Ana; Kemmerling Weis, Ulrike; Machado, Fabiana S.; Maya Arango, Juan (American Society for Microbiology, 2017)
      Current treatments for chronic Chagas cardiomyopathy, a disease with high mortality rates and caused by the protozoan Trypanosoma cruzi, are unsatisfactory. Myocardial inflammation, including endothelial activation, is ...
    • The ex vivo infection of human placental chorionic villi explants withtrypanosoma cruzi and toxoplasma ... 
      Muñoz, Lorena; Castillo, Christian; Carrillo, Ileana; Salinas, Andrea; Liempi, Ana; Droguett, Daniel; Maya Arango, Juan; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (2016)
      Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, and Toxoplasma gondii (T. gondii), responsible for Toxoplasmosis are two parasites that can cross the placental barrier. T. cruzi and T. gondii present ...
    • Trophoblast turnover in human placental chorionic villi explants induced by trypanosoma cruzi is mediated ... 
      Castillo, Christian; Muñoz, Lorena; Carrillo, Ileana; Droguett, Daniel; Liempi, Ana; Astudillo, Javier; Maya Arango, Juan; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (2016)
      Congenital Chagas’ disease, caused by the protozoan Trypanosoma cruzi (T. cruzi), is one of the major public health concerns in Latin America where more than one million women in fertile age are infected. During ...
    • Trypanosoma cruzi and toxoplasma gondii induce a differential MicroRNA profile in human placental explants 
      Medina, Lisvaneth; Castillo Rivas, Christian; Liempi, Ana; Guerrero Muñoz, Jesús; Rojas Pirela, Maura; Maya Arango, Juan Diego; Prieto, Humberto; Kemmerling Weis, Ulrike (Frontiers Media, 2020)
      Trypanosoma cruzi and Toxoplasma gondii are two parasites than can be transmitted from mother to child through the placenta. However, congenital transmission rates are low for T. cruzi and high for T. gondii. Infection ...
    • Trypanosoma cruzi induces cellular proliferation in the trophoblastic cell line BeWo 
      Droguett, Daniel; Carrillo, Ileana; Castillo, Christian; Gómez, Fresia; Negrete, Miguel; Liempi, Ana; Muñoz, Lorena; Kemmerling Weis, Ulrike; Galanti Garrone, Norbel; Maya Arango, Juan; Droguett, Daniel (Academic Press Inc., 2017)
      © 2016 Elsevier Inc.Congenital transmission of Trypanosoma cruzi (T. cruzi) is partially responsible for the progressive globalization of Chagas disease. During congenital transmission the parasite must cross the placental ...