Browsing by Author "fcda8685-b55d-41f7-856e-d98d2a4590c2"

Now showing items 1-6 of 6

    • 2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors 
      Lühr, Susan; Vilches Herrera, Marcelo; Fierro, Angélica; Ramsay, Rona R.; Edmondson, Dale E.; Reyes Parada, Miguel; Cassels Niven, Bruce; Iturriaga-Vásquez, Patricio (2010)
      2-Arylthiomorpholine and 2-arylthiomorpholin-5-one derivatives, designed as rigid and/or non-basic phenylethylamine analogues, were evaluated as rat and human monoamine oxidase inhibitors. Molecular docking provided insight ...
    • Blue-Fluorescent Probes for Lipid Droplets Based on Dihydrochromeno-Fused Pyrazolo- and Pyrrolopyridines 
      Becerra-Ruiz, Martín; Vargas, Victor; Jara, Patricio; Tirapegui, Cristian; Carrasco, Carlos; Núñez González, Marco; Lezana, Nicolás; Galdámez Silva, Antonio; Vilches-Herrera, Marcelo (Wiley-VCH Verlag, 2018)
      © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Lipid droplets (LDs) have been recognized as highly dynamic cellular organelles involved in important biological functions for the survival of organisms such as supplying ...
    • Diastereoselective synthesis of spirodihydrobenzofuran analogues of the natural product filifolinol 
      Becerra Ruiz, Martín; Galdámez Silva, Antonio; Modak, Brenda; Vilches Herrera, Marcelo (Wiley, 2020)
      Filifolinol is a natural occurring spirodihydrobenzofuran isolated from the resinous exudates of Heliotropium filifolium, a Chilean endemic shrub. Filifolinol and some of its derivatives have shown interesting biological ...
    • Influence of the bite natural angle of bidentate diphosphine ligands in the syngas-free branched hydroformylation ... 
      Vilches-Herrera, Marcelo; Concha-Puelles, Matias; Carvajal, Nicole; Molina, Juana; Santander, Rocio; Caroli Rezende, Marcos; Lühr, Susan (Elsevier B.V., 2018)
      © 2018 Elsevier B.V. The correlation between the activity, regio- and chemoselectivity of Rh-diphosphine catalyst and the ligand bite natural angle (βn) in the syngas-free hydroformylation of allyl cyanide was investigated. ...
    • Phytochemical Analysis of Alkaloids fron the Chilean Endemic Tree Cryptocarya Alba 
      Castro Saavedra, Sebastián; Fuentes Barros, Gonzalo; Tirapegui Calquín, Cristian; Acevedo Fuentes, Williams; Cassels Niven, Bruce; Barriga González, Andrés; Vilches Herrera, Marcelo (Sociedad Chilena Química, 2016)
      A phytochemical study of the roots and aerial parts of Cryptocarya alba (Mol.) Looser (Lauraceae), an endemic Chilean tree and the southernmost Cryptocarya species, led for the first time to the isolation and unambiguous ...
    • Reduction over condensation of carbonyl compounds through a transient hemiaminal intermediate using hydrazine 
      Vilches Herrera, Marcelo; Gallardo Fuentes, Sebastián; Aravena Opitz, Mauricio; Yáñez Sánchez, Mauricio; Jiao, Haijun; Holz, Jens; Börner, Armin; Lühr, Susan (American Chemical Society, 2020)
      Reduction of carbonyl moieties to the corresponding alcohol using simply hydrazine hydrate has been considerably unfeasible until now due to the well-known condensation reaction. However, herein, we report that using an ...