Now showing items 1-10 of 10

    • Oyarce, César; Cruz Gómez, Sebastián; Gálvez Cancino, Felipe Ignacio; Vargas, Pablo; Moreau, Hélène D.; Díaz Valdivia, Natalia; Díaz, Jorge; Salazar Onfray, Flavio; Pacheco, Rodrigo; Lennon Duménil, Ana María; Quest, Andrew F. G.; Lladser, Álvaro (Frontiers Media, 2017)
      Dendritic cell (DC) trafficking from peripheral tissues to lymph nodes (LNs) is a key step required to initiate T cell responses against pathogens as well as tumors. In this context, cellular membrane protrusions and the ...
    • Araos, Patricio; Prado, Carolina; Lozano, Mauricio; Figueroa, Stefanny; Espinoza, Alexandra; Berger, Thorsten; Mak, Tak W.; Jaisser, Frédéric; Pacheco, Rodrigo; Michea Acevedo, Luis; Amador, Cristián A. (Lippincott Williams and Wilkins, 2019)
      Background:Adaptive immunity is crucial in cardiovascular and renal inflammation/fibrosis upon hyperactivation of mineralocorticoid receptor. We have previously demonstrated that dendritic cells can respond to mineralocorticoid ...
    • Elgueta, Daniela; Contreras, Francisco; Prado, Carolina; Montoya, Andro; Ugalde, Valentina; Chovar, Ornella; Villagra, Roque; Henríquez, Claudio; Abellanas, Miguel A.; Aymerich, María S.; Franco, Rarael; Pacheco, Rodrigo (Frontiers Media S.A., 2019)
      Copyright © 2019 Elgueta, Contreras, Prado, Montoya, Ugalde, Chovar, Villagra, Henríquez, Abellanas, Aymerich, Franco and Pacheco. This is an open-access article distributed under the terms of the Creative Commons Attribution ...
    • Contreras, Francisco; Prado, Carolina; González, Hugo; Franz, Dafne; Osorio Barrios, Francisco; Osorio Olivares, Fabiola; Ugalde, Valentina; López, Ernesto; Elgueta, Daniela; Figueroa, Alicia; Lladser, Álvaro; Pacheco, Rodrigo (Amer Assoc Immunologists, 2016)
      Dopamine receptor D3 (DRD3) expressed on CD4(+) T cells is required to promote neuroinflammation in a murine model of Parkinson's disease. However, how DRD3 signaling affects T cell-mediated immunity remains unknown. In ...
    • Contreras, Francisco; Ríos del Prado, Carolina Alejandra; González, Hugo; Franz, Dafne; Osorio Barrios, Francisco; Osorio, Fabiola; Ugalde, Valentina; Lopez, Ernesto; Elgueta, Daniela; Figueroa, Alicia; Lladser, Álvaro; Pacheco, Rodrigo (American Association of Immunologists, 2016)
      Copyright © 2016 by The American Association of Immunologists, Inc.Dopamine receptor D3 (DRD3) expressed on CD4+ T cells is required to promote neuroinflammation in a murine model of Parkinson's disease. However, how DRD3 ...
    • Pardo, Evelyn; Carcamo, Claudia; Uribe San Martin, Reinaldo; Ciampi, Ethel; Segovia Miranda, Fabián; Curkovic Peña, Cristobal; Montecino, Fabián; Holmes, Christopher; Tichauer, Juan E.; Acuña, Eric; Osorio Barrios, Francisco; Castro, Marjorie; Cortes, Priscilla; Oyanadel, Claudia; Valenzuela, David M.; Pacheco, Rodrigo; Naves Pichuante, Rodrigo Antonio; Soza, Andrea; González, Alfonso (Public Library Science, 2017)
      Galectin-8 (Gal-8) is a member of a glycan-binding protein family that regulates the immune system, among other functions, and is a target of antibodies in autoimmune disorders. However, its role in multiple sclerosis (MS), ...
    • Medel, Bernardita; Costoya, Cristobal; Fernandez, Dominique; Pereda, Cristian; Lladser, Alvaro; Sauma, Daniela; Pacheco, Rodrigo; Iwawaki, Takao; Salazar Onfray, Flavio; Osorio, Fabiola (Frontiers Media S.A., 2019)
      The IRE1α/XBP1s signaling pathway is an arm of the unfolded protein response (UPR) that safeguards the fidelity of the cellular proteome during endoplasmic reticulum (ER) stress, and that has also emerged as a key regulator ...
    • Hevia, Daniel; Araos, Patricio; Prado, Carolina; Fuentes Luppichini, Eugenia; Rojas, Macarena; Alzamora Miranda, Rodrigo; Cifuentes Araneda, Flavia; González, Alexis A.; Amador, Cristian A.; Pacheco, Rodrigo; Michea Acevedo, Luis (Lippincott Williams & Wilkins, 2018)
      Increasing evidence shows that antigen-presenting cells (APCs) are involved in the development of inflammation associated to hypertension. However, the potential role of APCs in the modulation of renal sodium transport has ...
    • Hevia, Daniel; Araos, Patricio; Ríos del Prado, Carolina Alejandra; Luppichini, Eugenia Fuentes; Rojas, MacArena; Alzamora, Rodrigo; Cifuentes-Araneda, Flavia; González, Alexis A.; Amador, Cristian A.; Pacheco, Rodrigo; Michea Acevedo, Luis (Lippincott Williams and Wilkins, 2018)
      © 2017 The Authors.Increasing evidence shows that antigen-presenting cells (APCs) are involved in the development of inflammation associated to hypertension. However, the potential role of APCs in the modulation of renal ...
    • Doñas, Cristian; Carrasco, Macarena; Fritz, Macarena; Ríos del Prado, Carolina Alejandra; Tejón, Gabriela; Osorio Barrios, Francisco; Manríquez, Valeria; Reyes, Paz; Pacheco, Rodrigo; Bono Merino, María Rosa; Loyola, Alejandra; Rosemblatt Silber, Mario César (Academic Press, 2016)
      © 2016 The Authors As it has been established that demethylation of lysine 27 of histone H3 by the lysine-specific demethylase JMJD3 increases immune responses and thus elicits inflammation, we hypothesize that inhibition ...