Browsing by Author "Lavados Germain, Pablo Manuel"

Now showing items 21-40 of 41

    • Incidence, 30-day case-fatality rate, and prognosis of stroke in Iquique, Chile: a 2-year community-based ... 
      Lavados Germain, Pablo Manuel; Sacks, Claudio; Prina, Liliana; Escobar, Arturo; Tossi, Claudia; Araya, Fernando; Feuerhake Molina, Walter; Gálvez Moya, Marcelo; Salinas, Rodrigo; Alvarez, Gonzalo (LANCET, 2005-06-25)
      Background The epidemiology of stroke in Latin-American populations and variation of subtypes between communities are unclear. Our aim was to ascertain prospectively the incidence of first-ever stroke in the predominantly ...
    • Incidence, case-fatality rate, and prognosis of ischaemic stroke subtypes in a predominantly Hispanic-Mestizo ... 
      Lavados Germain, Pablo Manuel; Sacks, Claudio; Prina, Liliana; Escobar, Arturo; Tossi, Claudia; Araya, Fernando; Feuerhake, Walter; Gálvez, Marcelo; Salinas, Rodrigo; Álvarez, Gonzalo (Lancet Publishing Group, 2007)
      Background: Incidence of ischaemic stroke subtypes, classified by cause, seems to vary between communities. We aimed to prospectively ascertain the incidence of first-ever ischaemic stroke in a predominantly Hispanic-Mestizo ...
    • Influence of mannitol in acute intracerebral haemorrhage: Multivariate and propensity score analyses of INTERACT2 
      Wang, X.; Arima, H.; Y., J.; Zhang, S.; Wu, G.; Woodward, M.; Lavados Germain, Pablo Manuel; Stapf, C.; Robinson, T.; Heeley, E. (Wiley-Blackwell, 2015)
    • Influence of renal impairment on outcome for thrombolysis-treated acute ischemic stroke ENCHANTED (Enhanced ... 
      Carr, Susan J.; Wang, Xia; Olavarría, Verónica V.; Lavados Germain, Pablo Manuel; Rodríguez, Jorge A.; Kim, Jong S.; Lee, Tsong-Hai; Lindley, Richard I.; Pontes Neto, Octavio M.; Ricci, Stefano; Sato, Shoichiro; Sharma, Vijay K.; Woodward, Mark; Chalmers, John; Anderson, Craig S.; Robinson, Thompson G. (Lippincott Williams & Wilkins, 2017)
      Background and Purpose-Renal dysfunction (RD) is associated with poor prognosis after stroke. We assessed the effects of RD on outcomes and interaction with low- versus standard-dose alteplase in a post hoc subgroup analysis ...
    • Intracranial Angioplasty and Stent Placement After Stenting and Aggressive Medical Management for Preventing ... 
      Qureshi, Adnan I.; Al-Senani, Fahmi M.; Husain, Shakir; Janjua, Nazli A.; Lanzino, Giuseppe; Lavados Germain, Pablo Manuel; Nguyen, Thanh; Raymond, Jean; Shah, Qaisar A.; Suarez, Jose I.; Suri, M. Fareed K.; Tolun, Reha (2012)
      Objective: The results of prematurely terminated stenting and aggressive medical management for preventing recurrent stroke in intracranial stenosis (SAMMPRIS) due to excessively high rate of stroke and death in patients ...
    • Lipid-Lowering pretreatment and outcome following intravenous thrombolysis for acute ischaemic stroke: A ... 
      Minhas, Jatinder S.; Wang, Xia; Arima, Hisatomi; Bath, Philip M.; Billot, Laurent; Broderick, Joseph P.; Donnan, Geoffrey A.; Kim, Jong S.; Lavados Germain, Pablo Manuel; Lee, Tsong-Hai; Martins, Sheila Cristina Ouriques; Olavarría, Verónica V.; Pandian, Jeyaraj D.; Pontes Neto, Octavio Marques; Ricci, Stefano; Sato, Shoichiro; Sharma, Vijay K.; Thang, Nguyen H.; Wang, Ji-Guang; Woodward, Mark; Chalmers, John; Anderson, Craig S.; Robinson, Thompson G. (Karger, 2018)
      Background: Debate exists as to whether statin pretreatment confers an increased risk of 90-day mortality and symptomatic intracranial haemorrhage (sICH) in acute ischaemic stroke (AIS) patients treated with intravenous ...
    • Long-term adherence to national guidelines for secondary prevention of ischemic stroke: a prospective cohort ... 
      Muñoz Venturelli, Paula; Sacks, Claudio; Madrid, Eva; Lavados Germain, Pablo Manuel (National Stroke Association, 2014)
      Background: Clinical guidelines for the secondary prevention of ischemic stroke have been developed, but their publication is insufficient to make them effective. Our aim was to investigate adherence to Chilean guidelines, ...
    • Mannitol and Outcome in Intracerebral Hemorrhage Propensity Score and Multivariable Intensive Blood Pressure ... 
      Wang, Xia; Arima, Hisatomi; Yang, Jie; Zhang, Shihong; Wu, Guojun; Woodward, Mark; Muñoz Venturelli, Paula; Lavados Germain, Pablo Manuel; Stapf, Christian; Robinson, Thompson; Heeley, Emma; Delcourt, Candice; Lindley, Richard I.; Parsons, Mark; Chalmers, John; Anderson, Craig S. (Lippincott Williams & Wilkins, 2015)
      Background and Purpose Mannitol is often used to reduce cerebral edema in acute intracerebral hemorrhage but without strong supporting evidence of benefit. We aimed to determine the impact of mannitol on outcome among ...
    • Optimal achieved blood pressure in acute intracerebral hemorrhage: INTERACT2 
      Arima, Hisatomi; Heeley, Emma; Delcourt, Candice; Hirakawa, Yoichiro; Wang, Xia; Woodward, Mark; Robinson, Thompson; Stapf, Christian; Parsons, Mark; Lavados Germain, Pablo Manuel; Huang, Yining; Wang, Jiguang; Chalmers, John; Anderson, Craig S. (Lippincott Williams and Wilkins, 2015)
      Objectives: To investigate the effects of intensive blood pressure (BP) lowering according to baseline BP levels and optimal achieved BP levels in patients with acute intracerebral hemorrhage (ICH). Methods: INTERACT2 ...
    • Performance measures for in-hospital care of acute ischemic stroke in public hospitals in Chile 
      Hoffmeister, Lorena; Lavados Germain, Pablo Manuel; Comas, Merce; Vidal, Carolina; Cabello, Rodrigo; Castells, Xavier (BioMed Central, 2013)
      Background: The aim of this study were to describe acute care of ischemic stroke patients and adherence to performance measures, as well as the outcomes of these events, in a sample of patients treated in public hospitals in ...
    • Poor utility of grading scales in acute intracerebral hemorrhage: results from the INTERACT2 trial 
      Heeley, Emma; Anderson, Craig S.; Woodward, Mark; Arima, Hisatomi; Robinson, Thompson; Stapf, Christian; Parsons, Mark; Lavados Germain, Pablo Manuel; Huang, Yining; Wang, Yanxia; Crozier, Sophie; Parry Jones, Adrian; Wang, Jiguang; Chalmers, John (Wiley & Sons, 2015)
      Background Several simple clinical grading scores have been developed for intracerebral hemorrhage, primarily to predict 30-day mortality. Aims We aimed to determine the accuracy of three popular scores (original ...
    • Priorities to reduce the burden of stroke in Latin American countries 
      Ouriques Martins, Sheila C.; Sacks, Claudio; Hacke, Werner; Brainin, Michael; de Assis Figueiredo, Francisco; Marques Pontes-Neto, Octávio; Lavados Germain, Pablo Manuel; Marinho, Maria F.; Hoppe Wiegering, Arnold; Vaca McGhie, Diana; Cruz-Flores, Salvador; Ameriso, Seb (Lancet Publishing Group, 2019)
      The large and increasing burden of stroke in Latin American countries, and the need to meet the UN and WHO requirements for reducing the burden from non-communicable disorders (including stroke), brought together stroke ...
    • Prognostic Significance of Hyperglycemia in Acute Intracerebral Hemorrhage The INTERACT2 Study 
      Saxena, Anuhhav; Anderson, Craig S.; Wang, Xia; Sato, Shoichiro; Arima, Hisatomi; Chan, Edward; Muñoz Venturelli, Paula; Delcourt, Candice; Robinson, Thompson; Stapf, Christian; Lavados Germain, Pablo Manuel; Wang, Jiguang; Neal, Bruce; Chalmers, John; Heeley, Emma (LIPPINCOTT WILLIAMS & WILKINS, 2016)
      Background and Purpose- We aimed to determine associations of baseline blood glucose and diabetes mellitus with clinical outcomes in participants of the Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial ...
    • Rapid Blood Pressure Lowering According to Recovery at Different Time Intervals after Acute Intracerebral ... 
      Wang, Xia; Arima, Hisatomi; Al-Shahi Salman, Rustam; Woodward, Mark; Heeley, Emma; Stapf, Christian; Lavados Germain, Pablo Manuel; Robinson, Thompson; Huang, Yining; Wang, Jiguang; Delcourt, Candice; Anderson, Craig S. (Karger, 2015)
      Background and Purpose: Early intensive blood pressure (BP) lowering has been shown to improve functional outcome in acute intracerebral hemorrhage (ICH), but the treatment effect is modest and without a clearly defined ...
    • Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage 
      Anderson, Craig S.; Heeley, Emma; Huang, Yining; Wang, Jiguang; Stapf, Christian; Delcourt, Candice; Lindley, Richard; Robinson, Thompson; Lavados Germain, Pablo Manuel; Neal, Bruce; Hata, Jun; Arima, Hisatomi; Parsons, Mark; Li, Yuechun; Wang, Jinchao; Heritier, Stephane; Qiang, Li; Woodward, Mark; Simes, John; Davis, Stephen M.; Chalmers Barraza, John (Massachusetts Medical Society, 2013)
      Background Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. Methods We randomly assigned 2839 patients who had had a spontaneous ...
    • Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy ... 
      Huang, Yining; Sharma, Vijay K.; Robinson, Thompson; Lindley, Richard I.; Chen, Xiaoying; Kim, Jong Sung; Lavados Germain, Pablo Manuel; Olavarría, Verónica; Arima, Hisatomi; Fuentes, Sully; Nguyen, Huy Thang; Lee, Tsong-Hai; Parsons, Mark W.; Levi, Christopher; Demchuk, Andrew M.; Bath, Philip M.W.; Broderick, Joseph P.; Donnan, Geoffrey A.; Martins, Sheila; Pontes Neto, Octavio M.; Silva, Federico; Pandian, Jeyaraj; Ricci, Stefano; Stapf, Christian; Woodward, Mark; Wang, Jiguang; Chalmers, John; Anderson, Craig S. (World Stroke Organization, 2015)
      RationaleControversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogen activator (rt-PA) and degree of blood pressure (BP) control in acute ischaemic stroke (AIS). Asian studies suggest low-dose ...
    • Rationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy ... 
      Huang, Yining; Sharma, Vijay K.; Robinson, Thompson; Lindley, Richard I.; Chen, Xiaoying; Kim, Jong Sung; Lavados Germain, Pablo Manuel; Olavarría, Verónica; Arima, Hisatomi; Fuentes, Sully; Nguyen, Huy Thang; Lee, Tsong Hai; Parsons, Mark W.; Levi, Christopher; Demchuk, Andrew M. (Blackwell Publishing Ltd, 2015)
      © 2015 World Stroke Organization. Rationale: Controversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogen activator (rt-PA) and degree of blood pressure (BP) control in acute ischaemic stroke ...
    • Significance of Cerebral Small-Vessel Disease in Acute Intracerebral Hemorrhage 
      Sato, Shoichiro; Delcourt, Candice; Heeley, Emma; Arima, Hisatomi; Zhang, Shihong; Salman, Rustam Al-Shahi; Stapf, Christian; Woo, Daniel; Flaherty, Matthew L.; Vagal, Achala; Levi, Christopher; Davies, Leo; Wang, Jiguang; Robinson, Thompson; Lavados Germain, Pablo Manuel; Lindley, Richard I.; Chalmers, John; Anderson, Craig S. (LIPPINCOTT WILLIAMS & WILKINS, 2016)
      Background and Purpose- The significance of structural changes associated with cerebral small-vessel disease (SVD), including white matter lesions (WML), lacunes, and brain atrophy, to outcome from acute intracerebral ...
    • Socioeconomic and cardiovascular variables explaining regional variations in stroke mortality in Chile: An ... 
      Lavados Germain, Pablo Manuel; Díaz, Violeta; Jadue, Liliana; Olavarría, Verónica V.; Cárcamo, Daniel A.; Delgado, Iris (2011)
      Background: Regional differences in stroke mortality rates have been described in Chile. These could be related to the distribution of cardiovascular risk factors, the quality of medical care or socioeconomic status ...
    • Stroke units in Chile Unidades de tratamiento del ataque cerebrovascular (UTAC) en Chile 
      Lavados Germain, Pablo Manuel; Hoppe W, Arnold (2005)
      Stroke is a major public health problem in Chile, with an incidence similar to that of many industrialized nations, it accounts for 10% of all deaths and ranks 5 th in number of healthy years of life lost to a disease. ...