Browsing by Author "Maccioni Baraona, Ricardo"
Now showing items 21-40 of 53
-
Neumann, Karen F.; Rojo, Leonel; Navarrete, Leonardo P.; Farías, Gonzalo; Reyes, Paula; Maccioni Baraona, Ricardo (BENTHAM SCIENCE PUBL LTD, 2008-10)Hyperinsulinemia as well as type II diabetes mellitus are among the risk factors for Alzheimer´s disease (AD). However, the molecular and cellular basis that link insulin resistance disorders and diabetes with AD are far ...
-
Capote Jofre, Maria Carolina (1994)Existe abundante evidencia que los distintos filamentos que constituyen el citoesqueleto se encuentran interconectados, y que la trama de interacciones macromoleculares que se establecen entre ellos junto a su dinámica de ...
-
Zambrano, Angara; Otth, Carola; Mujica, Lorena; Concha, Ilona I.; Maccioni Baraona, Ricardo (BIOMED CENTRAL LTD, 2007-10-03)Background: Interleukin-3 (IL-3) is an important glycoprotein involved in regulating biological responses such as cell proliferation, survival and differentiation. Its effects are mediated via interaction with cell surface ...
-
Ramirez Gonzalez, Omar Alejandro (Universisdad de Chile, 2009)La quinasa dependientes de ciclina 5 (Cdk5) esta involucrada en proceso de migración, crecimiento neurótico y diferenciación neuronal. La actividad de Cdk5 en el sistema nervioso esta regulado por la interacción con sus ...
-
Morales, Inelia; Guzmán Martínez, Leonardo; Cerda Troncoso, Cristóbal; Farías, Gonzalo A.; Maccioni Baraona, Ricardo (Frontiers Research Foundation, 2014)Alzheimer disease (AD) is the most common cause of dementia in people over 60 years old. The molecular and cellular alterations that trigger this disease are still diffuse, one of the reasons for the delay in finding an ...
-
Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease Rojo, Leonel E.; Fernández, Jorge A.; Maccioni, Andrea A.; Jiménez, José M.; Maccioni Baraona, Ricardo (2008)During the past few years, an increasing set of evidence has supported the major role of deregulation of the interaction patterns between glial cells and neurons in the pathway toward neuronal degeneration. Neurons and ...
-
Neuroinflammation: Implications for the pathogenesis and molecular diagnosis of Alzheimer's disease Rojo, Leonel; Fernández Darraz, Jorge; Maccioni, Andrea A.; González Jiménez, José; Maccioni Baraona, Ricardo (ELSEVIER SCIENCE INC, 2007-05-31)During the past few years, an increasing set of evidence has supported the major role of deregulation of the interaction patterns between glial cells and neurons in the pathway toward neuronal degeneration. Neurons and ...
-
Orellana, Daniel I.; Quintanilla, Rodrigo A.; Maccioni Baraona, Ricardo (Elsevier B.V., 2006-10-21)The tumor necrosis factor alpha (TNFα) plays a dual role in producing either neurodegeneration or neuroprotection in the central nervous system. Despite that TNFα was initially described as a cell death inductor, ...
-
Maccioni Baraona, Ricardo (2002)
-
Maccioni Baraona, Ricardo; Tapia, José Pablo; Guzmán Martínez, Leonardo (Elsevier Inc., 2018)
-
Sáez, Estefanía T.; Pehar, Mariana; Vargas, Marcelo R.; Barbeito, Luis; Maccioni Baraona, Ricardo (WILEY-LISS, 2006-10)Reactive astrocytes surround amyloid depositions and degenerating neurons in Alzheimer's disease (AD). It has been previously shown that P-amyloid peptide induces inflammatory-like responses in astrocytes, leading to ...
-
Sáez, Estefanía T.; Pehar, Mariana; Vargas, Marcelo R.; Barbeito, Luis; Maccioni Baraona, Ricardo (2006)Reactive astrocytes surround amyloid depositions and degenerating neurons in Alzheimer's disease (AD). It has been previously shown that β-amyloid peptide induces inflammatory-like responses in astrocytes, leading to ...
-
Morales Gonzalez, Inelia (Universisdad de Chile, 2010)El mal de Alzheimer es una enfermedad neurovegetativa del cerebro, es la causa mas frecuente de demencia que afecta a los adultos mayores. En etapas avanzadas la enfermedad de Alzheimer (EA) produce la muerte masiva de ...
-
Guzmán, Leda; Bustos, Rodrigo; Maccioni Baraona, Ricardo (Kluwer Academic Publishers, 1994)The changes in the levels of microtubule-associated proteins (MAPs) during advanced embryonic stages, neonatal and adult organisms reflect the importance of these cytoskeletal proteins in relation to the morphogenesis of ...
-
Muñoz, Juan P.; Sánchez, Jaime R.; Maccioni Baraona, Ricardo (2003)Neuronal differentiation implies morphological and biochemical changes to generate a specialized neuron. N2A neuroblastoma cells can be promoted to undergo differentiation associated to neurites outgrowth, a process linked ...
-
Ramírez, C.; Alvarez, A.; García Abreu, J.; Gomes, F. C.A.; Moura-Neto, V.; Maccioni Baraona, Ricardo (Associacao Brasileira de Divulgacao Cientifica, 1999)As a result of recent investigations, the cytoskeleton can be viewed as a cytoplasmic system of interconnected filaments with three major integrative levels: self-assembling macromolecules, filamentous polymers, e.g., ...
-
Maccioni Baraona, Ricardo; Rojo, Leonel; Fernández, Jorge A.; Kuljis, Rodrigo O. (BLACKWELL, 2009)The idea that alterations in the brain immunomodulation are critical for Alzheimer’s disease (AD) pathogenesis provides the most integrative view on this cognitive disorder, considering that converging research lines ...
-
Orellana, Daniel I.; Quintanilla, Rodrigo A.; González Billault, Christian; Maccioni Baraona, Ricardo (Springer New York LLC, 2005)Recent studies show that inflammation has an active role in the onset of neurodegenerative diseases. It is known that in response to extracellular insults microglia and/or astrocytes produce inflammatory agents. These ...
-
Rojo, Leonel E.; Sjoberg, Marcela; Hernández, Paula; Zambrano, Cristian; Maccioni Baraona, Ricardo (HINDAWI PUBLISHING CORPORATION, 2006)Alzheimer's disease is the principal cause of dementia throughout the world and the fourth cause of death in developed economies. This brain disorder is characterized by the formation of brain protein aggregates, namely, ...
-
Carrasco Gallardo, Carlos; Guzmán, Leonardo; Maccioni Baraona, Ricardo (2012)Shilajit is a natural substance found mainly in the Himalayas, formed for centuries by the gradual decomposition of certain plants by the action of microorganisms. It is a potent and very safe dietary supplement, restoring ...