Browsing by Author "Soto, Claudio"

Now showing items 21-26 of 26

    • Reduction of prion infectivity in packed red blood cells 
      Morales, Rodrigo; Buytaert-Hoefen, Kimberley A.; González Romero, Dennisse; Castilla, Joaquín; Hansen, Eric T.; Hlavinka, Dennis; Goodrich, Raymond P.; Soto, Claudio (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008-12-12)
      The link between a new variant form of Creutzfeldt-Jakob disease (vCJD) and the consumption of prion contaminated cattle meat as well as recent findings showing that vCJD can be transmitted by blood transfusion have raised ...
    • Seeding of oligomers: new strategies for Alzheimer´s diagnosis and possible implications for the progression ... 
      Estrada Apablaza, Lisbell Dianne. (Universisdad de Chile, 2010)
      Alzheimer's disease (AD) is a complex neurodegenerative condition which has become a major public health problem because of its increasing prevalence, long duration and high cost of care. It is estimated than more than ...
    • Series de ahorro e ingreso por agente económico en Chile, 1960-1997 
      Bennett, Herman; Schmidt-Hebbel Dunker, Klaus; Soto, Claudio (Universidad de Chile. Facultad de Economía y Negocios, 2000-06)
      This paper presents new sector saving series for Chile. The annual series for 1960-1997 are disaggregated by six sectors: external sector, general government, public enterprises, central banks, private firms, and households. ...
    • Stressing out the ER: A role of the unfolded protein response in prion-related disorders 
      Hetz Flores, Claudio; Soto, Claudio (2006)
      Transmissible Spongiform Encephalopathies are fatal and infectious neurodegenerative diseases characterized by extensive neuronal apoptosis and the accumulation of an abnormally folded form of the cellular prion protein ...
    • The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo 
      Park, Kyung Won; Eun Kim, Gyoung; Morales, Rodrigo; Moda, Fabio; Moreno González, Inés; Concha Marambio, Luis; Lee, Amy S.; Hetz Flores, Claudio; Soto, Claudio (Nature Publishing Group, 2017)
      © The Author(s) 2017. Prion diseases are fatal neurodegenerative disorders affecting several mammalian species, characterized by the accumulation of the misfolded form of the prion protein, which is followed by the induction ...
    • Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis 
      Hetz Flores, Claudio; Lee, Ann Hwee; González Romero, Dennisse; Thielen, Peter; Castilla, Joaquín; Soto, Claudio; Glimcher, Laurie H. (2008)
      The unfolded protein response (UPR) is a conserved adaptive reaction that increases cell survival under endoplasmic reticulum (ER) stress conditions. X-box-binding protein-1 (XBP-1) is a key transcriptional regulator of ...