Browsing by Author "Maya Arango, Juan"

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    • Trypanosoma cruzi induces apoptosis in ex vivo infected human chorionic villi 
      Duaso, J.; Rojo, G.; Jaña, F.; Galanti Garrone, Norbel; Cabrera, G.; Bosco, C.; López Muñoz, Rodrigo; Maya Arango, Juan; Ferreira, J.; Kemmerling Weis, Ulrike (2011)
      Chagas' disease, produced by the haemoflagellated protozoan Trypanosoma cruzi (T. cruzi), is one of the most frequent endemic diseases in Latin America. In spite that in the past few years T. cruzi congenital transmission ...
    • Trypanosoma cruzi induces tissue disorganization and destruction of chorionic villi in an ex vivo infection ... 
      Duaso, J.; Rojo, G.; Cabrera, G.; Galanti Garrone, Norbel; Bosco, C.; Maya Arango, Juan; Morello Casté, Antonio; Kemmerling Weis, Ulrike (Elsevier, 2010)
      Congenital Chagas’ disease, endemic in Latin America and also present with lower frequency in other countries, is associated with premature labor, miscarriage, and placentitis. The mechanism of tissue invasion and infection ...
    • Trypanosoma cruzi induces trophoblast differentiation: A potential local antiparasitic mechanism of the ... 
      Liempi, A.; Castillo, C.; Duaso, J.; Droguett, D.; Sandoval, A.; Barahona, K.; Hernández, A.; Galanti Garrone, Norbel; Maya Arango, Juan; Kemmerling Weis, Ulrike (W.B. Saunders, 2014)
      Introduction: The congenital transmission of Trypanosoma cruzi (T. cruzi) is responsible for one-third of new Chagas disease cases each year. During congenital transmission, the parasite breaks down the placental barrier ...
    • Trypanosoma cruzi: Activities of lapachol and α- and β-lapachone derivatives against epimastigote and ... 
      Salas, Cristian; Tapia, Ricardo A.; Ciudad, Karina; Armstrong, Verónica; Orellana Bown, Myriam; Kemmerling Weis, Ulrike; Ferrada Parker, Jorge; Maya Arango, Juan; Morello Casté, Antonio (Elsevier Ltd, 2008-01-15)
      Derivatives of natural quinones with biological activities, such as lapachol, α- and β-lapachones, have been synthesized and their trypanocidal activity evaluated in vitro in Trypanosoma cruzi cells. All tested compounds ...
    • Trypanosoma cruzi: In vitro effect of aspirin with nifurtimox and benznidazole 
      López Muñoz, Rodrigo; Faúndez, Mario; Klein, Sebastián; Escanilla, Sebastián; Torres, Gloria; Lee-Liu, Dasfne; Ferrada Parker, Jorge; Kemmerling Weis, Ulrike; Orellana Bown, Myriam; Morello Casté, Antonio; Ferreira, Arturo; Maya Arango, Juan (ELSEVIER, 2010)
      Nifurtimox and benznidazole are the only active drugs against Trypanosoma cruzi; however, they have limited efficacy and severe side effects. During primoinfection, T. cruzi infected macrophages mount an antiparasitic ...