Browsing by Author "XX584907"

Now showing items 21-39 of 39

    • Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in ... 
      Sánchez, G.; Liberona, Leonel; Llanos Mansilla, Jorge; Sanhueza, E. M.; Giussani, Dino A.; Blanco, C. E.; Hanson, M. A.; Riquelme González, Raquel (CAMBRIDGE UNIV PRESS, 2002-10-01)
      The hypothesis that nitric oxide plays a key role in the regulation of adrenal blood flow and plasma concentrations of cortisol and catecholamines under basal and hypoxaemic conditions in the llama fetus was tested. At ...
    • Nitric oxide synthase activity in brain tissues from llama fetuses submitted to hypoxemia 
      Galleguillos, Marco; Valenzuela Pedevila, María Antonieta; Riquelme González, Raquel; Sanhueza, Emilia M.; Sánchez, Gina; Figueroa, Jorge P.; Llanos Mansilla, Jorge (ELSEVIER SCIENCE INC, 2001-06)
      The fetal llama (Lama glama; a species adapted to live in chronic hypoxia in the highlands of the Andes) did not increase cerebral blood flow and reduce the brain oxygen uptake during hypoxemia. Although nitric oxide (NO) ...
    • Perinatal cardiopulmonary adaptation to the thin air of the Alto Andino by a native Altiplano dweller, the llama 
      Reyes Catalán, Víctor; Herrera Videla, Emilio; Ebensperger Darrouy, Germán; Sanhueza Reinoso, Emilia; Giussani, D. A.; Llanos Mansilla, Jorge (American Physiological Society, 2020)
      Most mammals have a poor tolerance to hypoxia, and prolonged O-2 restriction can lead to organ injury, particularly during fetal and early postnatal life. Nevertheless, the llama (Lama Glama) has evolved efficient mechanisms ...
    • Plasma glucocorticoid and adrenocorticotropin concentrations measured serially in growth-retarded fetal lambs 
      Llanos Mansilla, Jorge; Rose, James C.; Creasy, Robert K.; Green, James R.; Serón Ferré, María (1979)
      We studied the fetal pituitray-adrenal axis in 9 growth retarded fetal lambs by serially measuring plasma glucocorticoids and ACTH concentrations from 115 to 140 days of gestation and adrenal blood flow at 138 days of ...
    • Plasmatic concentrations of ADMA and homocystein in llama (Lama glama) and regulation of arginase type II: ... 
      López, Vasthi; Moraga, Fernando A.; Llanos Mansilla, Jorge; Ebensperger Darrouy, Germán; Taborda, María I.; Uribe, Elena (Frontiers Media SA., 2018-05-29)
      There are animal species that have adapted to life at high altitude and hypobaric hypoxia conditions in the Andean highlands. One such species is the llama (Lama glama), which seem to have developed efficient protective ...
    • Potential adverse effects of antenatal melatonin as a treatment for intrauterine growth restriction: findings ... 
      González Candia, Alejandro; Véliz, Marcelino; Araya, Claudio; Quezada, Sebastián; Ebensperger Darrouy, Germán; Serón Ferré, María; Reyes, Roberto V.; Llanos Mansilla, Jorge; Herrera Videla, Emilio (Mosby-Elsevier, 2016)
      BACKGROUND: Intrauterine growth restriction is a condition in which the fetus has a birthweight and/or length <10th percentile for the gestational age. Intrauterine growth restriction can be associated with various causes, ...
    • Regional brain blood flow and cerebral hemispheric oxygen consumption during acute hypoxaemia in the Ilama fetus 
      Llanos Mansilla, Jorge; Riquelme, Raquel A.; Sanhueza, Emilia M.; Herrera Videla, Emilio; Cabello, Gertrudis; Giussani, Dino A.; Parer, Julian T. (2002)
      Unlike fetal animals of lowland species, the llama fetus does not increase its cerebral blood flow during an episode of acute hypoxaemia. This study tested the hypothesis that the fetal llama brain maintains cerebral ...
    • Repeated doses of the perfluorocarbon FC-100 improve lung function of preterm lambs 
      Moya, Fernando R.; Llanos Mansilla, Jorge; Ríos, Antonio M.; Riquelme, Raquel A.; Moraga, Fernando A.; Rubio, Lilian A.; Salvo, Hugo D.; Jacobs, Harris C. (Nature Publishing Group, 1997)
      Intratracheal administration of a single dose of the perfluorocarbon FC- 100 improves lung function in surfactant-deficient animals. In this study we compared the response to repeated doses of FC-100 (3 mL/kg 3% solution, ...
    • Revisiting the role of TRP, orai, and ASIC channels in the pulmonary arterial response to hypoxia 
      Reyes, Roberto V.; Castillo Galán, Sebastián; Hernández, Ismael; Herrera, Emilio A.; Ebensperger Darrouy, Germán; Llanos Mansilla, Jorge (Frontiers Media S.A., 2018)
      © 2018 Reyes, Castillo-Galán, Hernandez, Herrera, Ebensperger and Llanos. The pulmonary arteries are exquisitely responsive to oxygen changes. They rapidly and proportionally contract as arterial PO2 decrease, and they ...
    • Role of the RhoA/ROCK pathway in high-altitude associated neonatal pulmonary hypertension in lambs 
      López, Nandy; Ebensperger Darrouy, Germán; Herrera Videla, Emilio; Reyes, Roberto V.; Calaf, Gloria; Cabello, Gertrudis; Moraga, Fernando; Benaldo, Felipe A.; Díaz, Marcela; Parer, Julian T.; Llanos Mansilla, Jorge (Amer Physiological Soc, 2016)
      Exposure to high-altitude chronic hypoxia during pregnancy may cause pulmonary hypertension in neonates, as a result of vasoconstriction and vascular remodeling. We hypothesized that susceptibility to pulmonary hypertension, ...
    • Role of the α-adrenergic system in femoral vascular reactivity in neonatal llamas and sheep: A comparative ... 
      Moraga, Fernando A.; Reyes, Roberto V.; Herrera, Emilio A.; Riquelme, Raquel A.; Ebensperger Darrouy, Germán; Pulgar, Víctor M.; Parer, Julian T.; Giussani, Dino A.; Llanos Mansilla, Jorge (2011)
      Using an integrative approach at the whole animal, isolated vessels, and molecular levels, we tested the hypothesis that the llama, a species that undergoes pregnancy under the influence of the chronic hypoxia of high ...
    • Sildenafil Reverses Hypoxic Pulmonary Hypertension in Highland and Lowland Newborn Sheep 
      Herrera Videla, Emilio; Ebensperger Darrouy, Germán; Krause, Bernardo; Riquelme González, Raquel; Reyes, Roberto V.; Capetillo, María; González, Sergio; Parer, Julian T.; Llanos Mansilla, Jorge (International Pediatric Research Foundation, Inc., 2008)
      Perinatal exposure to chronic hypoxia induces sustained hypertension and structural and functional changes in the pulmonary vascular bed. We hypothesized that highland newborn lambs (HLNB, 3600 m) have a higher pulmonary ...
    • The circadian variation of prolactin in fetal sheep is affected by the seasons 
      Serón Ferré, María; Vergara, Marcela; Parraguez Gamboa, Víctor; Riquelme, Raquel; Llanos Mansilla, Jorge (1989)
      Plasma PRL concentration shows a circadian variation in fetal and adult sheep. In the adult sheep the presence of this variation depends on the season. In this paper we investigated whether season affects the presence of ...
    • The heme oxygenase-carbon monoxide system in the regulation of cardiorespiratory function at high altitude 
      Llanos Mansilla, Jorge; Ebensperger Darrouy, Germán; Herrera, Emilio A.; Reyes, Roberto V.; Cabello, Gertrudis; Díaz Díaz, Marcela Cecilia; Giussani, Dino A.; Parer, Julian T. (2012)
      Pulmonary arterial hypertension is one of the most serious pathologies that can affect the 140 million people living at altitudes over 2500. m. The primary emphasis of this review is pulmonary artery hypertension in mammals ...
    • The placental pursuit for an adequate oxidant balance between the mother and the fetus 
      Herrera, Emilio A.; Krause, Bernardo; Ebensperger Darrouy, Germán; Reyes, Roberto V.; Casanello, Paola; Parra Cordero, Mauro; Llanos Mansilla, Jorge (Frontiers Research Foundation, 2014)
      The placenta is the exchange organ that regulates metabolic processes between the mother and her developing fetus. The adequate function of this organ is clearly vital for a physiologic gestational process and a healthy ...
    • The role of neuropeptide Y in the ovine fetal cardiovascular response to reduced oxygenation 
      Sanhueza, Emilia M.; Johansen-Bibby, Anja A.; Fletcher, A. J W; Riquelme, Raquel A.; Daniels, Alejandro J.; Serón Ferré, María; Gaete, Cristián R.; Carrasco, Jorge E.; Llanos Mansilla, Jorge; Giussani, Dino A. (2003)
      This study investigated the role of neuropeptide Y (NPY) in mediating cardiovascular responses to reduced oxygenation in the late gestation ovine fetus by: (1) comparing the effects on the cardiovascular system of an ...
    • The role of nitric oxide in the cardiopulmonary response to hypoxia in highland and lowland newborn llamas 
      Reyes, Roberto V.; Díaz Díaz, Marcela Cecilia; Ebensperger Darrouy, Germán; Herrera, Emilio A.; Quezada, Sebastián A.; Hernández, Ismael; Sanhueza, Emilia M.; Parer, Julian T.; Giussani, Dino A.; Llanos Mansilla, Jorge (Blackwell Publishing Ltd, 2018)
      © 2018 The Physiological Society. Key points: Perinatal hypoxia causes pulmonary hypertension in neonates, including humans. However, in species adapted to hypoxia, such as the llama, there is protection against pulmonary ...
    • Use of fetal biometry to determine fetal age in late pregnancy in llamas 
      Herrera Videla, Emilio; Riquelme González, Raquel; Sanhueza, E. M.; Raggi Saini, Luis; Llanos Mansilla, Jorge (ELSEVIER SCIENCE BV, 2002-11-15)
      Sixty-three pregnant llamas of known breeding date were used in this study. Forty-six of them were submitted to surgery between 186 and 320 days of gestation (52-91% of average gestation period, respectively). Under general ...
    • α-melanocyte-stimulating hormone and adrenocorticotropin in the regulation of glucocorticoid secretion ... 
      Llanos Mansilla, Jorge; Ramachandran, Janakiraman; Creasy, Robert K.; Rudolph, Abraham M.; Serón Ferré, María (1979)
      To determine the role of other ACTH-like peptides in the regulation of glucocorticoid secretion in fetal sheep, we examined the responses of the adrenal gland of fetal and newborn sheep to comparable single doses of αMSH ...