Browsing by Author "XX606849"
Now showing items 21-26 of 26
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Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability Copaja, Miguel; Venegas, Daniel; Aranguiz, Pablo; Canales, Jimena; Vivar, Raúl; Avalos, Yennifer; García Nannig, Lorena; Chiong Lay, Mario; Olmedo, Ivonne; Catalán, Mabel; Leyton Campos, Lisette; Lavandero González, Sergio; Díaz Araya, Guillermo (Elsevier, 2012)Statins reduce the isoprenoids farnesyl and geranylgeranyl pyrophosphate, essential intermediates, which control a diversity of cellular events such as cytoskeleton integrity, adhesion, migration and viability. Cardiac ...
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Ortiz, Rina; Díaz, Jorge; Díaz Valdivia, Natalia; Martínez Meza, Samuel; Simón, Layla; Contreras Orellana, Pamela; Lobos González, Lorena; Guerrero, Simón; Leyton Campos, Lisette; Quest, Andrew F. G. (Elsevier, 2020)In advanced stages of cancer disease, caveolin-1 (CAV1) expression increases and correlates with increased migratory and invasive capacity of the respective tumor cells. Previous findings from our laboratory revealed that ...
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Díaz, N.; Leyton Campos, Lisette; Quest, Andrew F. G. (Wiley, 2017)
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Burgos Bravo, F.; Wilson Moya, Christian; Quest, Andrew F. G.; Leyton Campos, Lisette (Wiley, 2017)
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Díaz Valdivia, Natalia; Díaz, Jorge; Contreras, Pamela; Campos, América; Rojas Celis, Victoria; Burgos Ravanal, Renato; Lobos González, Lorena; Torres Gómez, Vicente; Pérez, Viviana I.; Frei, Balz; Leyton Campos, Lisette; Quest, Andrew F. G. (Nature, 2020)Caveolin-1 (CAV1) enhanced migration, invasion, and metastasis of cancer cells is inhibited by co-expression of the glycoprotein E-cadherin. Although the two proteins form a multiprotein complex that includes beta-catenin, ...
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Kong, Milene; Muñoz, Nicolás; Valdivia, Alejandra; Álvarez, Ávaro; Herrera Molina, Rodrigo; Cárdenas, Areli; Schneider, Pascal; Burridge, Keith; Quest, Andrew F. G.; Leyton Campos, Lisette (Elsevier, 2013)Cell adhesion to the extracellular matrix proteins occurs through interactions with integrins that bind to Arg-Gly-Asp (RGD) tripeptides, and syndecan-4, which recognizes the heparin-binding domain of other proteins. ...