Browsing by Author "González Billault, Christian"
Now showing items 21-40 of 46
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(Public Library Science, 2015)Neuronal death in Parkinson's disease (PD) is often preceded by axodendritic tree retraction and loss of neuronal functionality. The presence of non-functional but live neurons opens therapeutic possibilities to recover ...
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(Public Library of Science, 2015)© 2015 Aguirre et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in anymedium, provided the original ...
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(Springer, 2011)Studies in post-mortem tissues of patients with Parkinson’s disease (PD) and in mice treated with 6-hydroxydopamine have shown a decrease in the length of axon and dendrites of striatal neurons. However, the etiology of ...
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(AMER SOC CELL BIOLOGY, 2010-08-09)Cultured neurons obtained from MAP1B-deficient mice have a delay in axon outgrowth and a reduced rate of axonal elongation compared with neurons from wild-type mice. Here we show that MAP1B deficiency results in a ...
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MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression (2013)The microtubule-associated protein 1B (MAP1B) plays critical roles in neurite growth and synapse maturation during brain development. This protein is well expressed in the adult brain. However, its function in mature ...
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(2011)Microtubule-associated protein 1B (MAP1B) is prominently expressed during early stages of neuronal development, and it has been implicated in axonal growth and guidance. MAP1B expression is also found in the adult brain ...
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(Wiley Periodicals, Inc., 2004)Microtubule-associated protein 1B is the first MAP to be expressed during the development of the nervous system. Several different approaches have revealed that MAP1B function is associated with microtubule and actin ...
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(2007)Microtubule-associated protein 1B (MAP1B) is the first microtubule- associated protein to be expressed during nervous system development. MAP1B belongs to a large family of proteins that contribute to the stabilization ...
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(Universidad de Chile, 2009)FONDECYT, Proyecto N° 1060040
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(BMC, 2022)Background Aging is characterized by a progressive loss of capacities linked to fundamental alterations/damage in multiple cellular and molecular pathways. It is the most significant risk factor for all non-communicable ...
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(PERGAMON-ELSEVIER SCIENCE LTD, 2004-06-01)Oxidative stress has been demonstrated to produce modifications in several intracellular proteins that lead to alterations in their activities. Alzheimer's disease is related to an increase of oxidative stress markers, ...
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(2004)Oxidative stress has been demonstrated to produce modifications in several intracellular proteins that lead to alterations in their activities. Alzheimer's disease is related to an increase of oxidative stress markers, ...
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(Wiley-Blackwell, 2016)Cyclin-dependent kinase 5 (CDK5) plays important roles in synaptic function. Its unregulated over-activation has been, however, associated with neurodegeneration in Alzheimer's disease. Our previous studies revealed that ...
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(Wiley & Sons, 2015)CDK5 plays an important role in neurotransmission and synaptic plasticity in the normal function of the adult brain, and dysregulation can lead to Tau hyperphosphorylation and cognitive impairment. In a previous study, we ...
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(Public Library Science, 2015)Prenatal stress causes predisposition to cognitive and emotional disturbances and is a risk factor towards the development of neuropsychiatric conditions like depression, bipolar disorders and schizophrenia. The extracellular ...
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(John Wiley and Sons Inc., 2016)© 2016 Wiley Periodicals, Inc. Neurons are highly polarized cells that contain specialized subcellular domains involved in information transmission in the nervous system. Specifically, the somatodendritic compartment ...
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(International Society for Neurochemistry, 2014)Neuronal cells are characterized by the presence of two confined domains, which are different in their cellular properties, biochemical functions and molecular identity. The generation of asymmetric domains in neurons ...
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(Society for Neuroscience, 2016)© 2016 the authors. Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat ...
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(SOC BIOLGIA CHILE, 2011)Epithelial and neuronal cells are highly asymmetric, with discrete regions responsible for different roles that underlie the generation of specific compartments within cells that are distinct in biochemical composition, ...
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(Frontiers Media, 2015)A proper balance between chemical reduction and oxidation (known as redox balance) is essential for normal cellular physiology. Deregulation in the production of oxidative species leads to DNA damage, lipid peroxidation ...
