Browsing by Author "Alfaro Valdés, Hilda M."

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    • Mechanical Properties of Chaperone BiP, the Master Regulator of the Endoplasmic Reticulum 
      Alfaro Valdés, Hilda M.; Burgos Bravo, Francesca; Casanova Morales, Nathalie; Quiroga Roger, Diego; Wilson Moya, Christian A.M. (IntechOpen, 2018)
      Immunoglobulin heavy-chain-binding protein (BiP protein) is a 75-kDa Hsp70 monomeric ATPase motor that plays broad and crucial roles maintaining proteostasis inside the cell. Its malfunction has been related with the ...
    • Posttranslational Protein Translocation through Membranes at the Single-Molecule Level 
      Quiroga Roger, Diego; Alfaro Valdés, Hilda M.; Wilson Moya, Christian A.M. (Cambridge University Press, 2022)
      Protein secretion studies started in the 1950s with George Palade’s electron microscopy (EM) work (Palade, 1952, 1975). Protein secretion is a very relevant process because more than 30 percent of synthesized proteins work ...