Browsing by Author "Altamirano, Francisco"

Now showing items 1-14 of 14

    • Altered ROS production, NF-kappa B activation and interleukin-6 gene expression induced by electrical ... 
      Henríquez Olguín, Carlos; Altamirano, Francisco; Valladares, Denisse; López, José; Allen, Paul; Jaimovich Pérez, Enrique (Elsevier, 2015)
      Duchenne muscular dystrophy is a fatal X-linked genetic disease, caused by mutations in the dystrophin gene, which cause functional loss of this protein. This pathology is associated with an increased production of reactive ...
    • Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation ... 
      Henríquez Olguín, Carlos; Altamirano, Francisco; Valladares, Denisse; López, José R.; Allen, Paul D.; Jaimovich Pérez, Enrique (Elsevier, 2015)
      Duchenne muscular dystrophy is a fatal X-linked genetic disease, caused by mutations in the dystrophin gene, which cause functional loss of this protein. This pathology is associated with an increased production of reactive ...
    • Cav1.1 controls frequency-dependent events regulating adult skeletal muscle plasticity 
      Jorquera, Gonzalo; Altamirano, Francisco; Contreras Ferrat, Ariel Eduardo; Almarza, Gonzalo; Buvinic Radic, Sonja; Jacquemond, Vincent; Jaimovich Pérez, Enrique; Casas Atala, Mariana (The Company of Biologists, 2013)
      An important pending question in neuromuscular biology is how skeletal muscle cells decipher the stimulation pattern coming from motoneurons to define their phenotype as slow or fast twitch muscle fibers. We have previously ...
    • Electrical Stimuli Release ATP to Increase GLUT4 Translocation and Glucose Uptake via PI3Kg-Akt-AS160 in ... 
      Osorio Fuentealba, César; Contreras Ferrat, Ariel Eduardo; Altamirano, Francisco; Espinosa Escalona, Berta; Li, Qing; Niu, Wenyan; Lavandero González, Sergio; Klip, Amira; Jaimovich Pérez, Enrique (American Diabetes Association, 2013)
      Skeletal muscle glucose uptake in response to exercise is preserved in insulin-resistant conditions, but the signals involved are debated. ATP is released from skeletal muscle by contractile activity and can autocrinely ...
    • Elevation of NO Increases Ca2+ Entry and Resting Ca2+ and Na+ Concentrations in Skeletal Muscle Cells 
      Robin, Gaelle; Altamirano, Francisco; Zhang, Rui; Jaimovich Pérez, Enrique; Allen, Paul D.; López, José R. (Cell Press, 2015)
      Protein S-nitrosylation is a reversible post-translational modification and can have profound effects on protein function in skeletal muscle. S-nitrosylation has been proposed to exert regulatory effects on ion channels ...
    • Erratum 2: Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 ... 
      Altamirano, Francisco; Oyarce, César; Silva, Patricia; Toyos, Marcela; Wilson, Carlos; Lavandero González, Sergio; Uhlen, P.; Estrada, M. (BIOSCIENTIFICA LTD, 2009-09)
      Correction.
    • Fibroblast Primary Cilia Are Required for Cardiac Fibrosis 
      Villalobos, Elisa; Criollo Céspedes, Alfredo; Schiattarella, Gabriele G.; Altamirano, Francisco; French, Kristin M.; May, Herman I.; Jiang, Nan; Nguyen, Ngoc Uyen Nhi; Romero, Diego; Roa, Juan Carlos; García Nannig, Lorena; Díaz Araya, Guillermo; Morselli, Eugenia; Ferdous, Anwarul (NLM (Medline), 2019)
      BACKGROUND: The primary cilium is a singular cellular structure that extends from the surface of many cell types and plays crucial roles in vertebrate development, including that of the heart. Whereas ciliated cells have ...
    • Nitrosative stress drives heart failure with preserved ejection fraction 
      Schiattarella, Gabriele G.; Altamirano, Francisco; Tong, Dan; French, Kristin M.; Villalobos, Elisa; Kim, Soo Young; Luo, Xiang; Jiang, Nan; May, Herman I.; Wang, Zhao V.; Hill, Theodore M.; Mammen, Pradeep; Huang, Jian; Lee, Dong I.; Hahn, Virginia; Sharma, Kavita; Kass, David A.; Lavandero González, Sergio; Gillette, Thomas G.; Hill, Joseph A. (Nature Publishing Group, 2019)
      Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with high morbidity and mortality for which there are no evidence-based therapies. Here we report that concomitant metabolic and hypertensive ...
    • NOX2-Dependent ROS Production is Essential for the Response to Endurance Exercise in Skeletal Muscle 
      Henríquez Olguín, Carlos; Valladares Ide, Denisse; Díaz Vegas, Alexis; Utreras Mendoza, Yildy; Campos, Cristian; Llanos Vidal, Paola; Contreras Ferrat, Ariel Eduardo; Espinosa Escalona, Alejandra; Altamirano, Francisco; Arias Calderón, Manuel (Federation of American Societies for Experimental Biology, 2015)
    • Polycystin-1 is required for insulin-like growth factor 1-induced cardiomyocyte hypertrophy 
      Fernández, Carolina; Torrealba, Natalia; Altamirano, Francisco; Garrido Moreno, Valeria Soraya; Vásquez Trincado, César; Flores Vergara, Raúl Alejandro; López Crisosto, Camila; Ocaranza, María Paz; Chiong Lay, Mario Martin; Pedrozo Cibils, Zully Rocío Evangelina; Lavandero González, Sergio (Public Library Science, 2021)
      Cardiac hypertrophy is the result of responses to various physiological or pathological stimuli. Recently, we showed that polycystin-1 participates in cardiomyocyte hypertrophy elicited by pressure overload and mechanical ...
    • Polycystin-1 regulates cardiomyocyte mitophagy 
      Ramírez Sagredo, Andrea Soledad; Quiroga, Clara; Garrido Moreno, Valeria Soraya; López Crisosto, Camila; Leiva Navarrete, Sebastián Rolando; Norambuena Soto, Ignacio Estebán; Ortiz Quintero, Jose Jafet; Díaz Vesga, Magda C.; Pérez, William; Hendrickson, Troy; Parra Ortiz, Valentina Maria; Pedrozo Cibils, Zully Rocio Evangelina; Altamirano, Francisco; Chiong Lay, Mario Martin; Lavandero Gonzalez, Sergio Alejandro (Wiley, 2021)
      Polycystin-1 (PC1) is a transmembrane protein found in different cell types, including cardiomyocytes. Alterations in PC1 expression have been linked to mitochondrial damage in renal tubule cells and in patients with ...
    • RpoS and RpoN are involved in the growth-dependent regulation of rfaH transcription and O antigen expression ... 
      Bittner, Mauricio; Saldías, Soledad; Altamirano, Francisco; Valvano, Miguel A.; Contreras, Inés (ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD, 2004-01)
      We reported earlier that the production of 0 antigen lipopolysaccharide (LPS) by Salmonella enterica serovar Typhi (Salmonella typhi) increases at the onset of stationary phase and correlates with a growth-regulated ...
    • Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway 
      Altamirano, Francisco; Oyarce, César; Silva, Patricio; Toyos, Marcela; Wilson, Carlos; Lavandero González, Sergio; Uhlen, L.; Estrada, M. (BIOSCIENTIFICA LTD, 2009-08)
      Elevated testosterone concentrations induce cardiac hypertrophy but the molecular mechanisms are poorly understood. Anabolic properties of testosterone involve in increase in protein synthesis. The mammalian target of ...
    • Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ... 
      Schiattarella, Gabriele G.; Altamirano, Francisco; Young Kim, Soo; Tong, Dan; Ferdous, Anwarul; Piristine, Hande; Dasgupta, Subhajit; Wang, Xuliang; French, Kristin M.; Villalobos, Elisa; Spurgin, Stephen B.; Waldman, Maayan; Jiang, Nan; May, Herman I.; Hill, Theodore M.; Luo, Yuxuan; Yoo, Heesoo; Zaha, Vlad G.; Lavandero González, Sergio Alejandro; Gillette, Thomas G.; Hill, Joseph A. (Nature, 2021)
      Heart failure with preserved ejection fraction (HFpEF) is now the dominant form of heart failure and one for which no efficacious therapies exist. Obesity and lipid mishandling greatly contribute to HFpEF. However, molecular ...