Browsing by Author "Alvarez, Lautaro D."

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    • Synthesis and GABA(A) receptor activity of oxygen-bridged neurosteroid analogs 
      Alvarez, Lautaro D.; Veleiro, Adriana S.; Baggio, Ricardo F.; Garland, María Teresa; Edelsztein, Valeria C.; Coirini, Héctor; Burton, Gerardo (2008)
      Three analogs of neuroactive steroids were prepared (4-6) in which 1,11- or 11,19-oxygen bridges give a constrained conformation. Their 3D structures were obtained by ab initio calculations and in the case of 3 ...