Browsing by Author "Bórquez, Daniel A."

Now showing items 1-3 of 3

    • Inflaming the brain with iron 
      Urrutia Vargas, Pamela Joselyn; Bórquez, Daniel A.; Núñez González, Marco Tulio (MDPI, 2021)
      Iron accumulation and neuroinflammation are pathological conditions found in several neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD). Iron and inflammation are intertwined in a ...
    • New players in neuronal Iron homeostasis: insights from CRISPRi studies 
      Bórquez, Daniel A.; Castro, Francisco; Núñez González, Marco Tulio; Urrutia, Pamela J. (MDPI, 2022)
      Selective regional iron accumulation is a hallmark of several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. The underlying mechanisms of neuronal iron dyshomeostasis have been studied, ...
    • Searching for novel Cdk5 substrates in brain by comparative phosphoproteomics of wild type and Cdk5-/- mice 
      Contreras Vallejos, Erick; Utreras Puratich, Elías; Bórquez, Daniel A.; Prochazkova, Michaela; Terse, Anita; Jaffe, Howard; Toledo, Andrea; Arruti, Cristina; Pant, Harish C.; Kulkarni, Ashok B.; González Billault, Christian (Public Library of Science, 2014)
      Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly ...