Browsing by Author "Benítez, Diego"

Now showing items 1-4 of 4

    • Anti-trypanosomatid benzofuroxans and deoxygenated analogues: Synthesis using polymer-supported triphenylphosphine, ... 
      Castro, Diego; Boiani, Lucía; Benítez, Diego; Hernández, Paola; Merlino, Alicia; Gil, Carmen; Olea Azar, Claudio; González, Mercedes; Cerecetto, Hugo; Porcal, Williams (ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER, 2009-12)
      Hybrid vinylthio-, vinylsulfinyl-, vinylsulfonyl- and vinylketo-benzofuroxans developed as anti-trypanosomatid agents, against Trypanosoma cruzi and Leishmania spp., have showed low micromolar IC50 values. The synthetic ...
    • Initial studies on mechanism of action and cell death of active N-oxide-containing heterocycles in Trypanosoma ... 
      Benítez, Diego; Casanova, Gabriela; Cabrera, Gonzalo; Galanti Garrone, Norbel; Cerecetto, Hugo; González, Mercedes (Cambridge University Press, 2014)
      Chagas disease, endemic in 21 countries across Latin America, kills more people in the region each year than any other parasite-borne disease. Therapeutic options have problems ranging from toxicity, poor efficacy, drug ...
    • Study of Trypanosoma cruzi epimastigote cell death by NMR-visible mobile lipid analysis 
      Benítez, Diego; Pezaroglo, Horacio; Martínez, Verónica; Casanova, Gabriela; Cabrera Vallejos, Gonzalo; Galanti Garrone, Norbel; González, Mercedes; Cerecetto, Hugo (CAMBRIDGE UNIV PRESS, 2012-04)
      Cell death mechanisms in Trypanosoma cruzi have not been disclosed in detail though different conventional techniques have been used in the classification of parasite-cell death type. Nuclear magnetic resonance (NMR) has ...
    • Uso y percepción de conjuntos de viviendas sociales en la comuna de Curacaví 
      Benítez, Diego (Universidad de Chile, 2023)
      Esta investigación examina el uso y la percepción de los espacios comunitarios y barriales en tres conjuntos de viviendas sociales en la comuna de Curacaví, provincia de Melipilla. Se realizó una encuesta presencial a 60 ...