Browsing by Author "Berríos Cárcamo, Pablo"
Now showing items 1-7 of 7
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(Wiley-Blackwell, 2016)Background: A number of studies have shown that acetaldehyde synthesized in the brain is necessary to induce ethanol (EtOH) reinforcement in naive animals (acquisition phase). However, after chronic intake is achieved ...
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(Blackwell Publishing Ltd, 2019)(R/S)-Salsolinol is a full agonist of the μ-opioid receptor (μOR) Gi protein pathway via its (S)-enantiomer and is functionally selective as it does not promote β-arrestin recruitment. Compared to (S)-salsolinol, the ...
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(Frontiers Media S.A., 2017)© 2017 Berríos-Cárcamo, Quintanilla, Herrera-Marschitz, Vasiliou, Zapata-Torres and Rivera-Meza. Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, ...
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(2012)Dopamine (DA) condenses, at least in vitro, with acetaldehyde, the primary metabolite of ethanol, to form the regioisomers salsolinol (SAL) and isosalsolinol (isoSAL). An alternative in vivo route to SAL, requiring a ...
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(Universidad de Chile, 2013-01)Recientemente, se demostró que la metabolización de etanol a acetaldehído es indispensable para que su consumo sea reforzante; sin embargo, no se conoce el mecanismo cerebral por el cual se produce este efecto. Se ha ...
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(Oxford Univ Press, 2015)
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(Elsevier Inc., 2014)© 2014 Elsevier Inc.Salsolinol is formed non-enzymatically when ethanol-derived acetaldehyde binds to dopamine, yielding 2 distinct products, i.e., salsolinol and isosalsolinol. Early animal studies, revealing that salsolinol ...
