Among all the proposed pathogenic mechanisms to understand the etiology of Alzheimer's disease (AD), increased oxidative stress seems to be a robust and early disease feature where many of those hypotheses converge. However, ...

El factor neurotrófico derivado del cerebro (BDNF) es clave para la plasticidad sináptica hipocampal y la memoria espacial. La unión de BDNF a su receptor TrkB activa cascadas de señalización intracelular que involucran ...