Browsing by Author "Caballero, Julio"
Now showing items 1-6 of 6
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(Taylor & Francis, 2020)Alzheimer s disease (AD) is the most common form of dementia involving Ab and tau protein. So far, AD cure remains elusive, but considering that AD progresses throughout tau pathology, which turns tau protein an appropriate ...
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(Elsevier, 2014)In this Letter we present a new probe, (E)-7-(diethylamino)-2-oxo-2H-chromene-3-carbaldehyde oxime (JB), which can detect Cu2+ ions in HEPES buffer under physiological conditions. Benesi–Hildebrand and Job plots demonstrate ...
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(Taylor & Francis Ltd., 2021)Parkinson’s disease (PD) is a neurodegenerative disorder that affects adult people whose treatment is palliative. Thus, we decided to test three dammarane triterpenes 1, 1a, 1b, and we determined that 1 and 1a inhibit ...
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(2013)A new coumarin-based ‘turn-off’ fluorescent probe, 7-(diethylamino)-N-(1,3-dihydroxy-2-(hydroxymethyl) propan-2-yl)-2-oxo-2H-chromene-3-carboxamide (AGD) was synthesized. This compound is highly selective for ferrous ...
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(Taylor & Francis, 2017)Alzheimer’s disease is a common tauopathy where fibril formation and aggregates are the hallmark of the disease. Efforts targeting amyloid-b plaques have succeeded to remove plaques but failed in clinical trials to improve ...
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(Springer, 2015)The three-dimensional quantitative structure-activity relationship (3D QSAR) models have many applications, although the inherent complexity to understand the results coming from 3D-QSAR arises the necessity of new insights ...
