Now showing items 1-3 of 3

    • Caballero, Leonardo; Mena, Juan; Morales Alvarez, Aurora; Kogan Bocian, Marcelo; Melo, Francisco (Amer Chemical Soc, 2015)
      We present a method based on atomic force microscopy (AFM) to assess the work of adhesion between the interfaces of gold AFM tips functionalized with three peptides derived from beta-sheet breaker LPFFD [CLPFFD-NH2 (i(0)) ...
    • Cornejo, Alberto; Caballero, Julio; Simirgiotis, Mario; Torres, Vanessa; Sánchez, Luisa; Díaz, Nicolás; Guimaraes, Marcela; Hernández, Marcos; Areche Medina, Carlos Alberto; Alfaro, Sergio; Caballero, Leonardo; Melo, Francisco (Taylor & Francis Ltd., 2021)
      Parkinson’s disease (PD) is a neurodegenerative disorder that affects adult people whose treatment is palliative. Thus, we decided to test three dammarane triterpenes 1, 1a, 1b, and we determined that 1 and 1a inhibit ...
    • González, Camila; Cartagena, Constanza; Caballero, Leonardo; Melo, Francisco; Areche Medina, Carlos Alberto; Cornejo, Alberto (MDPI, 2021)
      Neurodegenerative disorders, including Tauopathies that involve tau protein, base their pathological mechanism on forming proteinaceous aggregates, which has a deleterious effect on cells triggering an inflammatory ...