Browsing by Author "Cabezas, David"

Now showing items 1-2 of 2

    • Antiproliferative and proapoptotic activities of aza-annulated naphthoquinone analogs 
      Suárez Rozas, Cristian; Simpson, Sebastián; Fuentes Retamal, Sebastián; Catalán, Mabel; Ferreira, Jorge; Theoduloz, Cristina; Mella, Jaime; Cabezas, David; Cassels Niven, Bruce; Yáñez, Claudia; Castro Castillo, Vicente (Elsevier Ltd, 2019)
      © 2018 1,4-Naphthoquinone derivatives have been widely documented with regard to their biological properties, and particularly their anticancer activities. In the 9,10-anthraquinone family, aza-annulation involving one of ...
    • Novel N-arylsulfonylindoles targeted as ligands of the 5-HT6 receptor. Insights on the influence of C-5 ... 
      Arrieta Rodríguez, Loreto; Espinoza Rosales, Daniela; Vera, Gonzalo; Cho, Young Hwa; Cabezas, David; Vásquez Velásquez, David Reinaldo; Mella Raipán, Jaime; Lagos, Carlos F.; Recabarren Gajardo, Gonzalo (MDPI, 2021)
      A new series of twenty-two C-5 substituted N-arylsulfonylindoles was prepared with the aim of exploring the influence of C-5 substitution on 5-HT6 receptor affinity. Eleven compounds showed moderate to high affinity at the ...