Browsing by Author "Carrasco, M. Angélica"

Now showing items 1-5 of 5

    • A role for reactive oxygen/nitrogen species and iron on neuronal synaptic plasticity 
      Hidalgo Tapia, María Cecilia; Carrasco, M. Angélica; Muñoz, Pablo; Núñez González, Marco (2007)
      A great body of experimental evidence collected over many years indicates that calcium has a central role in a variety of neuronal functions. In particular, calcium participates in synaptic plasticity, a neuronal process ...
    • Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in ... 
      Paula Lima, Andrea; Adasme, Tatiana; San Martín Rovirosa, Carol; Sebollela, Adriano; Hetz Flores, Claudio; Carrasco, M. Angélica; Ferreira, Sergio T.; Hidalgo Tapia, María Cecilia (2011)
      Soluble amyloid β-peptide oligomers (AβOs), increasingly recognized as causative agents of Alzheimer's disease (AD), disrupt neuronal Ca2+ homeostasis and synaptic function. Here, we report that AβOs at sublethal concentrations ...
    • High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca2+ release and ... 
      Riquelme, Denise; Alvarez, Alvaro; Leal, Nancy; Adasme, Tatiana; Espinoza, Italo; Valdés, Juan Antonio; Troncoso, Natalia; Hartel, Steffen; Segura Hidalgo, Jorge Antonio; Hidalgo Tapia, María Cecilia; Carrasco, M. Angélica (2011)
      Neuronal electrical activity increases intracellular Ca2+ concentration and generates reactive oxygen species. Here, we show that high frequency field stimulation of primary hippocampal neurons generated Ca 2+ signals with ...
    • NF-κB activation by depolarization of skeletal muscle cells depends on ryanodine and IP3 receptor-mediated ... 
      Valdés, Juan Antonio; Segura Hidalgo, Jorge Antonio; Galaz, José Luis; Puentes, Natalia; Silva, Mónica; Jaimovich Pérez, Enrique; Carrasco, M. Angélica (2007)
      Depolarization of skeletal muscle cells by either high external K + or repetitive extracellular field potential pulses induces calcium release from internal stores. The two components of this release are mediated by either ...
    • Redox control of brain calcium in health and disease 
      Hidalgo Tapia, María Cecilia; Carrasco, M. Angélica (2011)
      Calcium ion is a highly versatile cellular messenger. Calcium signals-defined as transient increments in intracellular-free calcium concentration-elicit a multiplicity of responses that depend on cell type and signal ...