Browsing by Author "Carrasquel Ursulaez, Willy"

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    • A BK (Slo1) channel journey from molecule to physiology 
      Contreras, Gustavo F.; Castillo, Karen; Enrique, Nicolás; Carrasquel Ursulaez, Willy; Castillo, Juan Pablo; Milesi, Verónica; Neely, Alan; Alvarez, Osvaldo; Ferreira, Gonzalo; Gonzalez, Carlos; Latorre, Ramón (Taylor and Francis Inc., 2013)
      Calcium and voltage-activated potassium (BK) channels are key actors in cell physiology, both in neuronal and non-neuronal cells and tissues. Through negative feedback between intracellular Ca2+ and membrane voltage, BK ...
    • Determination of the stoichiometry between alpha- and gamma 1 subunits of the BK channel using LRET 
      Carrasquel Ursulaez, Willy; Alvarez, Osvaldo; Bezanilla, Francisco; Latorre, Ramón (Cell Press, 2018)
      Two families of accessory proteins, beta and gamma, modulate BK channel gating and pharmacology. Notably, in the absence of internal Ca2+, the gamma 1 subunit promotes a large shift of the BK conductance-voltage curve to ...