Browsing by Author "Castillo, Christian"
Now showing items 1-11 of 11
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Carrillo, Ileana; Nonato Rabelo, Rayane Aparecida; Barbosa, César; Rates, Mariana; Fuentes Retamal, Sebastián Andrés; González Herrera, Fabiola; Guzmán Rivera, Daniela Inés; Quintero, Helena; Kemmerling Weis, Ulrike; Castillo, Christian; Machado, Fabiana; Díaz Araya, Guillermo; Maya, Juan (Public Library Science, 2021)Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America and is widely distributed worldwide because of migration. In 30% of cases, after years of infection and in the absence of treatment, ...
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Droguett, Daniel; Castillo, Christian; Leiva, Elba; Theoduloz, Cristina; Schmeda Hirschmann, Guillermo; Kemmerling Weis, Ulrike (Spandidos Publ, 2015)Oral squamous cell carcinoma (OSCC) is the most common form of head and neck cancer, and oxidative damage is associated with the development of OSCCs. Antioxidants have therefore been proposed for use as chemoprotective ...
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Rojas, Diego A.; Urbina, Fabiola; Moreira Ramos, Sandra; Castillo, Christian; Kemmerling Weis, Ulrike; Lapier, Michel; Maya Arango, Juan; Solari Illescas, Aldo; Maldonado Maldonado, Edio (Public Library Science, 2018)Trypanosoma cruzi is exposed during its life to exogenous and endogenous oxidative stress, leading to damage of several macromolecules such as DNA. There are many DNA repair pathways in the nucleus and mitochondria ...
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Castillo, Christian; Ramírez Toloza, Galia; Valck Calderón, Carolina Eliana; Aguilar, Lorena; Maldonado, Ismael; Rosas, Carlos; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike; Ferreira Vigouroux, Luis Arturo (PLOS Neglected Tropical Diseases, 2013)Background: 9 million people are infected with Trypanosoma cruzi in Latin America, plus more than 300,000 in the United States, Canada, Europe, Australia, and Japan. Approximately 30% of infected individuals develop ...
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Castillo, Christian; Villarroel, Arturo; Duaso, Juan; Galanti Garrone, Norbel; Cabrera Vallejos, Gonzalo; Maya Arango, Juan; Kemmerling Weis, Ulrike (Elsevier, 2013)Chagas‘ disease is caused by the haemophlagelated protozoan Trypanosoma cruzi (T. cruzi). During congenital transmission the parasite breaks down the placental barrier, however studies about the physiopathology of this ...
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Araneda, Sebastián; Castillo, Christian; Venegas, Bernardo; Kemmerling, Ulrike (SciELO Comision Nacional de Investigacion Cientifica Y Tecnologica (CONICYT), 2020)
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Molina Berríos, Alfredo Enrique; Campos Estrada, Carolina; Henríquez, Natalia; Faúndez, Mario; Torres, Gloria; Castillo, Christian; Escanilla, Sebastián; Kemmerling Weis, Ulrike; Morello Casté, Antonio; López Muñoz, Rodrigo; Maya Arango, Juan (PLoS, 2013)Chagas’ disease, produced by Trypanosoma cruzi, affects more than 8 million people, producing approximately 10,000 deaths each year in Latin America. Migration of people from endemic regions to developed countries has ...
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Rojo, Gemma; Castillo, Christian; Duaso, Juan; Liempi, Ana; Droguett Ossa, Daniel; Galanti Garrone, Norbel; Maya Arango, Juan; López Muñoz, Rodrigo; Kemmerling Weis, Ulrike (Elsevier, 2014)Nifurtimox (Nfx) and Benznidazole (Bnz) are the only available drugs in use for the treatment of Chagas disease. These drugs are recommended but not fully validated in evidence-based medicine and reports about the ...
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Liempi Manquel, Ana; Droguett Ossa, Daniel; Castillo, Christian; Gómez, Fresia; Negrete, Miguel; Carrillo, Ileana; Galanti Garrone, Norbel; Kemmerling Weis, Ulrike (Elsevier, 2015)
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Liempi, Ana; Castillo, Christian; Cerda, Mauricio; Droguett, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study the physiopathology ...
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Liempi Manquel, Ana; Castillo, Christian; Cerda Villablanca, Mauricio; Droguett Ossa, Daniel; Duaso, Juan; Barahona, Katherine; Hernández, Ariane; Díaz Luján, Cintia; Fretes, Ricardo; Härtel, Steffen; Kemmerling Weis, Ulrike (Elsevier, 2015)Chagas disease is an endemic, neglected tropical disease in Latin America that is caused by the protozoan parasite Trypanosoma cruzi. In vitro models constitute the first experimental approach to study the physiopathology ...