Browsing by Author "Castro, Ariel F."

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    • Rheb Promotes Cancer Cell Survival Through p27Kip1-Dependent Activation of Autophagy 
      Campos, Tania; Ziehe, Javiera; Palma, Mario; Escobar, David; Tapia Pineda, Julio; Pincheira, Roxana; Castro, Ariel F. (Wiley and Sons, 2016)
      We previously found that the small GTPase Rheb regulates the cell-cycle inhibitor p27KIP1 (p27) in colon cancer cells by a mTORC1-independent mechanism. However, the biological function of the Rheb/p27 axis in cancer ...