Browsing by Author "Castro, Isabel"

Now showing items 1-4 of 4

    • Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated ... 
      Bahamondes, Verónica; Albornoz, Amelina; Aguilera, Sergio; Alliende, Cecilia; Molina, Claudio; Castro, Isabel; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Barrera, María José; González, Sergio; Sánchez, Marianela; Härtel, Steffen; Hermoso Ramello, Marcela; Leyton Martínez, Cecilia; González Burgos, María Julieta (WILEY-BLACKWELL, 2011-10)
      Objective. Oral and ocular dryness are frequent and serious symptoms of Sjogren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in ... 
      Castro, Isabel; Aguilera, Sergio; Brockhausen, Inka; Alliende, Cecilia; Quest, Andrew F. G.; Molina, Claudio; Urzúa Tobar, Ulises; Mandel, Ulla; Bahamondes, Verónica; Barrera, María José; Sánchez, Marianela; González, Sergio; Hermoso Ramello, Marcela; Leyton Martínez, Cecilia; González Burgos, María Julieta (Oxford University Press, 2012)
      Objectives. To determine the expression and enzymatic activities of sulphotransferases involved in mucin hyposulphation in labial salivary glands (LSGs) from SS patients and to correlate sulphotransferase activity with ...
    • Pro-inflammatory cytokines enhance ERAD and ATF6 alpha pathway activity in salivary glands of Sjogren's ... 
      Barrera, María José; Aguilera, Sergio; Castro, Isabel; Cortés Araya, Juan Eliecer; Bahamondes Lorca, Verónica; Quest, Andrew F. G.; Molina, Claudio; González, Sergio; Hermoso Ramello, Marcela; Urzúa Tobar, Ulises; Leyton, Cecilia; González Burgos, María Julieta (Elsevier, 2016)
      Salivary gland (SG) acinar-cells are susceptible to endoplasmic reticulum (ER) stress related to their secretory activity and the complexity of synthesized secretory products. SGs of Sji5gren's syndrome patients (SS)-patients ...
    • Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular ... 
      Barrera, María José; Aguilera, Sergio; Veerman, Enno; Quest, Andrew F. G.; Díaz Jiménez, David; Urzúa Tobar, Ulises; Cortés Araya, Juan Eliecer; González, Sergio; Castro, Isabel; Molina, Claudio; Bahamondes, Verónica; Leyton, Cecilia; Hermoso Ramello, Marcela; González Burgos, María Julieta (Oxford Univ Press, 2015)
      Objectives. A hallmark characteristic of SS patients is the ectopic presence of the mucins MUC5B and MUC7 in the extracellular matrix of salivary glands that have lost apical basolateral acinar-cell polarity. This study ...