Browsing by Author "Castro, Lorena"

Now showing items 1-3 of 3

    • Hepatobiliary manifestations in inflammatory bowel disease: a practical approach 
      Núñez Figueroa, Paulina; Castro, Fabiola; Mezzano, Gabriel; Quera, Rodrigo; Díaz, Diego; Castro, Lorena (Baishideng Publishing, 2022)
      Inflammatory bowel diseases (IBD) are associated with various hepatobiliary disorders. They can occur at any moment in the course of the disease or associated with the treatment. The prevalence of liver dysfunction can ...
    • Novel Gallate Triphenylphosphonium Derivatives with Potent Antichagasic Activity 
      Cortés, Leonel A.; Castro, Lorena; Pesce Reyes, Bárbara; Maya Arango, Juan; Ferreira, Jorge; Castro Castillo, Vicente; Parra, Eduardo; Jara, José A.; López Muñoz, Rodrigo (Public Library Science, 2015)
      Chagas disease is one of the most neglected tropical diseases in the world, affecting nearly 15 million people, primarily in Latin America. Only two drugs are used for the treatment of this disease, nifurtimox and benznidazole. ...
    • Pentamidine antagonizes the benznidazole's effect in vitro, and lacks of synergy in vivo: Implications about ... 
      Seguel, Verónica; Castro, Lorena; Reigada, Chantal; Cortés, Leonel; Díaz, María V.; Miranda, Mariana R.; Pereira, Claudio A.; Lapier, Michel; Campos Estrada, Carolina; Morello Casté, Antonio; Kemmerling Weis, Ulrike; Maya, Juan D.; Lopez Muñoz, Rodrigo (Elsevier, 2016)
      Benznidazole is the first-line drug used in treating Chagas disease, which is caused by the parasite Trypanosoma cruzi (T. cruzi). However, benznidazole has limited efficacy and several adverse reactions. Pentamidine is ...