Breast cancer is the most common cause of death among women. While there have been significant improvements in diagnosis and treatment, the spread of cancer to other areas of the body remains the primary reason for mortality. ...

Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a matricellular protein that modulates interactions between cells and their microenvironment. SPARC is expressed during extracellular matrix remodeling ...