Browsing by Author "Cerpa Castro, Leslie"

Now showing items 1-5 of 5

    • Pharmacodynamic polymorphisms 
      Martínez Olguín, Matías; Cerpa Castro, Leslie; Morales Varela, Nelson; Quiñones Sepúlveda, Luis (Springer, 2021)
    • Pharmacogenomics: basis and milestones 
      Cerpa Castro, Leslie; Varela Figueroa, Nelson; Martínez Olguín, Matías; Quiñones Sepúlveda, Luis (Springer, 2021)
      The genomic interindividual heterogeneity for proper pharmacotherapy remains a significant challenge for research, clinical decision-making, and the design of clinical trials. Translation of the obtained genomic information ...
    • Pharmacogenomics: challenges and future perspectives 
      Quiñones Sepúlveda, Luis; Martínez Olguín, Matías; Cerpa Castro, Leslie; Varela Figueroa, Nelson (Springer, 2021)
      Pharmacogenetics is the science of understanding how genetic variability influences drug treatment outcomes and generally refers to the effects of a single genetic marker on pharmacokinetics and pharmacodynamics of ...
    • Pharmacogenomics: genetic polymorphisms 
      Varela Figueroa, Nelson; Cerpa Castro, Leslie; Martínez Olguín, Matías; Quiñones Sepúlveda, Luis (Springer, 2021)
      It has been estimated that the human genome harbors about 30,000 protein-coding genes. Within these proteins we find transporters, metabolizing enzymes, and therapeutic drug targets. The analysis of human genomic ...
    • Pharmacokinetic polymorphisms 
      Martínez Olguín, Matías; Cerpa Castro, Leslie; Varela Figueroa, Nelson; Quiñones Sepúlveda, Luis (Springer, 2021)
      A polymorphism is a genetic variant that leads to at least two non-rare phenotypes with a frequency of 1% or greater in a population. When the variant is in a gene that codifies proteins involved in drug absorption, ...