Browsing by Author "Cho, Young Hwa"

Now showing items 1-2 of 2

    • New pyridone-based derivatives as cannabinoid receptor type 2 agonists 
      Faúndez Parraguez, Manuel; Alarcón Miranda, Carlos; Cho, Young Hwa; Pessoa Mahana, Hernan Armando; Gallardo Garrido, Carlos; Chung, Hery; Faúndez, Mario; Pessoa Mahana, David (MDPI, 2021)
      The activation of the human cannabinoid receptor type II (CB2R) is known to mediate analgesic and anti-inflammatory processes without the central adverse effects related to cannabinoid receptor type I (CB1R). In this work ...
    • Novel N-arylsulfonylindoles targeted as ligands of the 5-HT6 receptor. Insights on the influence of C-5 ... 
      Arrieta Rodríguez, Loreto; Espinoza Rosales, Daniela; Vera, Gonzalo; Cho, Young Hwa; Cabezas, David; Vásquez Velásquez, David Reinaldo; Mella Raipán, Jaime; Lagos, Carlos F.; Recabarren Gajardo, Gonzalo (MDPI, 2021)
      A new series of twenty-two C-5 substituted N-arylsulfonylindoles was prepared with the aim of exploring the influence of C-5 substitution on 5-HT6 receptor affinity. Eleven compounds showed moderate to high affinity at the ...