Microdeletions of the Y chromosome have been observed in some patients with cryptorchidism and severe defects of spermatogenesis. We investigated whether microdeletions of the Y chromosome may be present in patients with ...

© 2015, Rev Med Chile. All rights reserved. Background A secular trend towards a younger age of puberty onset has been reported in Chilean girls. Aim: To evaluate the age of onset of puberty and prevalence of early puberty ...

Polycystic ovary syndrome (PCOS) is one of the most common endocrine conditions in women. PCOS may be more challenging to diagnose during adolescence due to an overlap with the physiological events of puberty, which are ...

© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons LtdBackground: Recent studies have suggested that there is an earlier age of onset of puberty in healthy boys. However, no study has determined the age of pubertal ...

Background: Congenital hypopituitarism is an uncommon cause of hypophyseal insufficiency. It is less common than growth hormone deficiency, which has an incidence of 1:4.000 to 1:8.000 live newborns. Early diagnosis of ...

Insulinoma is a very uncommon tumor in children, with an incidence in adults of 2 per million inhabitants.Clinical manifestations include neuroglycopenic or autonomic manifestations due to hypoglycemia. Wedescribe 2 pediatric ...