Browsing by Author "Cortés Troncoso, Juan"

Now showing items 1-4 of 4

    • Actividad GSH-transferásica citosólica de hígado de rata : susceptibilidad a iones de hierro 
      Cortés Troncoso, Juan (Universidad de Chile, 2007)
      Previamente hemos demostrado que el sistema Cu2+/ascorbato puede inhibir la actividad enzimática de algunas proteínas tiólicas a través de dos mecanismos: oxidación inducida por ROS y unión inespecífica de Cu2+ a ...
    • DPPH and oxygen free radicals as pro-oxidant of biomolecules 
      Letelier Muñoz, María Eugenia; Molina Berríos, Alfredo Enrique; Cortés Troncoso, Juan; Jara Sandoval, José; Holst, Marianne; Palma, Karina; Montoya, Margarita; Miranda, Dante; González Lira, Víctor (PERGAMON-ELSEVIER SCIENCE LTD, 2008-03)
      Numerous investigations exist about the alterations that oxygen free radicals can provoke on biomolecules; these modifications can be prevented and/or reversed by different antioxidants agents. On the other hand, ...
    • Mechanisms underlying the inhibition of the cytochrome P450 system by copper ions 
      Letelier, M. E.; Faúndez, M.; Jara Sandoval, José; Molina Berríos, Alfredo Enrique; Cortés Troncoso, Juan; Aracena Parks, Paula; Marín Catalán, Rigoberto (2009)
      Copper toxicity has been associated to the capacity of free copper ions to catalyze the production of superoxide anion and hydroxyl radical, reactive species that modify the structure and/or function of biomolecules. In ...
    • Nitroaryl-1,4-dihydropyridines as antioxidants against rat liver microsomes oxidation induced by iron/ascorbate, ... 
      Letelier Muñoz, María Eugenia; Entrala Alrruiz, Paz Andrea; López Alarcón, Camilo; González Lira, Víctor; Molina Berríos, Alfredo Enrique; Cortés Troncoso, Juan; Jara Sandoval, José; Santander, P.; Núñez Vergara, Luis (PERGAMON-ELSEVIER SCIENCE, 2007-12)
      1,4-Dihydropyridines (DHPs) used in the treatment of cardiovascular diseases, are calcium channel antagonists and also antioxidant agents. These drugs are metabolized through cytochrome P-450 oxidative system, majority ...