Browsing by Author "Corvalán, Alejandro H."

Now showing items 1-10 of 10

    • Epstein–Barr virus infection in lung cancer: insights and perspectives 
      Osorio, Julio C.; Blanco Santana, Rancés; Corvalán, Alejandro H.; Muñoz, Juan P.; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2022)
      Lung cancer (LC) is the leading cause of cancer death worldwide. Tobacco smoke is the most frequent risk factor etiologically associated with LC, although exposures to other environmental factors such as arsenic, radon or ...
    • Helicobacter pylori and epigenetic mechanisms underlying gastric carcinogenesis 
      Valenzuela, Manuel A.; Canales, Jimena; Corvalán, Alejandro H.; Quest, Andrew F. G. (Baishideng Publishing Group Inc., 2015)
      The sequence of events associated with the development of gastric cancer has been described as "the gastric precancerous cascade". This cascade is a dynamic process that includes lesions, such as atrophic gastritis, ...
    • High-risk human papillomavirus and epstein-barr virus coinfection: a potential role in head and neck carcinogenesis 
      Blanco, Rancés; Carrillo Beltrán, Diego; Corvalán, Alejandro H.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary A subset of carcinomas that arise in the head and neck region show a viral etiology. In fact, a subgroup of oropharyngeal cancers are caused by some types of human papillomavirus (HPV), so-called high-risk ...
    • Human papillomavirus in breast carcinogenesis: a passenger, a cofactor, or a causal agent? 
      Blanco, Rances; Carrillo Beltrán, Diego Antonio; Muñoz, Juan P.; Corvalán, Alejandro H.; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary Breast cancer (BC) is the most frequent tumor in women worldwide. A minority of BC patients have a family history of the disease, suggesting the importance of environmental and lifestyle factors. Human ...
    • Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor ... 
      Saavedra, Kathleen; Valbuena, José; Olivares, Wilda; Marchant, María José; Rodríguez, Andrés; Torres Estay, Verónica; Carrasco Avino, Gonzalo; Guzmán, Leda; Aguayo González, Francisco; Roa, Juan Carlos; Corvalán, Alejandro H. (Public Library Science, 2015)
      Reprimo (RPRM), a downstream effector of p53-induced cell cycle arrest at G2/M, has been proposed as a putative tumor suppressor gene (TSG) and as a potential biomarker for non-invasive detection of gastric cancer (GC). ...
    • MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer (vol 9, 114, 2017) 
      Sandoval Bórquez, Alejandra; Polakovicova, Iva; Carrasco Véliz, Nicolás; Lobos González, Lorena; Riquelme, Ismael; Carrasco Avino, Gonzalo; Bizama Soto, Carolina del Carmen; Norero, Enrique; Owen, Gareth I.; Roa Strauch, Juan Carlos; Corvalán, Alejandro H. (BMC, 2021)
    • Noncoding Genomics in Gastric Cancer and the Gastric Precancerous Cascade: Pathogenesis and Biomarkers 
      Sandoval Bórquez, Alejandra; Saavedra, Kathleen; Carrasco Avino, Gonzalo; García Bloj, Benjamin; Fry, Jacqueline; Wichmann, Ignacio; Corvalán, Alejandro H. (Hindawi Publishing, 2015)
      Gastric cancer is the fifth most common cancer and the third leading cause of cancer-related death, whose patterns vary among geographical regions and ethnicities. It is a multifactorial disease, and its development depends ...
    • Role of pirin, an oxidative stress sensor protein, in epithelial carcinogenesis 
      Pérez Domínguez, Francisco Javier; Carrillo Beltrán, Diego Antonio; Blanco Santana, Rancés; Muñoz, Juan P.; León Cruz, Grettell; Corvalán, Alejandro H.; Urzúa Tobar, Ulises de la Cruz; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary Pirin is a protein which is detected at low levels in normal tissues. However, it is detected at high levels in multiple cancers, particularly in melanomas, cervical cancer or squamous cell lung carcinomas. ...
    • Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024 
      Ferreccio, Catterina; Roa, Juan Carlos; Bambs, Claudia; Vives, Alejandra; Corvalán, Alejandro H.; Cortés, Sandra; Foerster, Claudia; Acevedo, Johanna; Huidobro, Andrea; Passi, Alvaro; Toro, Pablo; Covacevich, Yerko; Cruz, Rolando de la; Koshiol, Jill; Olivares, Mauricio; Miquel, Juan Francisco; Cruz, Francisco; Silva, Raúl; Quest, Andrew F. G.; Kogan Bocian, Marcelo; Castro, Pablo F.; Lavandero González, Sergio (BioMed Central, 2016)
      Background: Maule Cohort (MAUCO), a Chilean cohort study, seeks to analyze the natural history of chronic diseases in the agricultural county of Molina (40,000 inhabitants) in the Maule Region, Chile. Molina's population ...
    • Tobacco smoke activates human papillomavirus 16 p97 promoter and cooperates with high-risk E6/E7 for oxidative ... 
      Peña, Nelson; Carrillo, Diego; Muñoz, Juan P.; Chnaiderman, Jonás; Urzúa, Ulises; León, Oscar; Tornesello, Maria L.; Corvalán, Alejandro H.; Soto Rifo, Ricardo; Aguayo, Francisco (Public Library of Science, 2015)
      We have previously shown a functional interaction between human papillomavirus type 16 (HPV-16) E6 and E7 oncoproteins and cigarette smoke condensate (CSC) in lung cells suggesting cooperation during carcinogenesis. The ...