Browsing by Author "Del Villar, Eugenia"
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Vega, Patricio; Gaule, Carlos; Mancilla, Jerson; Del Villar, Eugenia (1993)1. Liver microsomes from alloxan or streptozotocin diabetic rats displayed differential drug metabolizing abilities in vitro. 2. Only streptozotocin liver microsomes exhibited changes in the cytochrome P-450 normal spectral ...
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Letelier Muñoz, María Eugenia; Sánchez, Emilio; Del Villar, Eugenia (1984)1. 1. Comparative studies of the actions of morphine in different mammals have shown that Octodon degus presents an unusual tolerance to this compound. 2. 2. Morphine glucuronidation and N-demethylation in microsomal ...
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Del Villar, Eugenia; Gaule, Carlos; Vega, Patricio (1995)1. 1. Streptozotocin-induced diabetes produced significant changes on the drug metabolizing enzyme machinery of rat kidney microsomes. 2. 2. It reduced the cytochrome P-450 content by 30%, this effect being reversed by ...
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Letelier Muñoz, María Eugenia (Universidad de Chile, 1982)En este trabajo se hace una comparación entre la rata Wistar y el Octodon degus, comúnmente llamado degú, de los efectos farmacológicos del pentobarbital y del metabolismo de la morfina y varios xenobióticos. La ...
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Orellana, Myriam; Valdés, Elena; Del Villar, Eugenia (1997)Microsomal lauric acid hydroxylation and fatty acid peroxisomal β-oxidation were studied in hepatic subcellulant preparations from streptozotocin-induced diabetic and diabetic insulin-treated rats. The liver microsomes of ...