Browsing by Author "Elorza, Álvaro A."

Now showing items 1-2 of 2

    • CD73 ectonucleotidase restrains CD8+T cell metabolic fitness and anti-tumoral activity 
      Briceño Catalán, Pedro Felipe; Rivas Yáñez, Elizabeth Camila; Rosemblatt Bono, Mariana Violeta; Parra Tello, Brian Josué; Farías, Paula; Vargas, Leonardo; Simon Zegers, María Valeska; Cárdenas, César; Lladser, Álvaro; Salazar Onfray, Flavio Andrés; Elorza, Álvaro A.; Rosemblatt Silber, Mario César; Bono Merino, María Rosa; Sauma Mahaluf, Daniela Macarena (Frontiers Media, 2021)
      CD39 and CD73 are ectoenzymes that dephosphorylate ATP into its metabolites; ADP, AMP, and adenosine, and thus are considered instrumental in the development of immunosuppressive microenvironments. We have previously shown ...
    • Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by ... 
      Arriagada, Alejandro A.; Albornoz, Eduardo; Opazo, María Cecilia; Becerra, Álvaro; Vidal, Gonzalo; Fardella, Carlos; Michea Acevedo, Luis; Carrasco, Nancy; Simón, Felipe; Elorza, Álvaro A.; Bueno, Susan M.; Kalergis, Alexis M.; Riedel, Claudia A. (Endocrine Society, 2015)
      Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cells is mainly regulated ...