Browsing by Author "Farfán Urzúa, Mauricio Javier"
Now showing items 1-13 of 13
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Canales López, Cristina (Universidad de Chile, 2012-08)La Leucemia Linfoblástica Aguda (LLA) es la neoplasia más común en niños, siendo la 6-mercaptopurina (6-MP) una droga que cumple un rol fundamental para el tratamiento de esta neoplasia. Sin embargo, se han asociado al ...
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Izquierdo Tramon, Mariana Andrea; López, Joaquín; Gallardo Schall, Pablo Alfredo; Vidal Álvarez, Roberto Mauricio; Ossa, Juan C.; Farfán Urzúa, Mauricio Javier (Frontiers Media, 2022)BackgroundDiarrheagenic E. coli (DEC) pathogenicity relies on the interaction of bacteria with the host's gut environment, which is regulated by the resident microbiota. Previously, we identified indicative bacterial species ...
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George Carreño, Sergio Andrés; Aguilera, Ximena; Gallardo Schall, Pablo Alfredo; Farfán Urzúa, Mauricio Javier; Lucero Álvarez, Yalda Cecilia; Torres, Juan Pablo; Vidal Álvarez, Roberto Mauricio; O'Ryan Gallardo, Miguel Luis (Frontiers Media, 2022)Gut microbiota composition during the first years of life is variable, dynamic and influenced by both prenatal and postnatal factors, such as maternal antibiotics administered during labor, delivery mode, maternal diet, ...
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Saitz Rojas, Waleska Lisette; Montero, David A.; Pardo, Mirka; Araya, Daniela; Fuente, Marjorie de la; Hermoso Ramello, Marcela Alejandra; Farfán Urzúa, Mauricio Javier; Ginard, Daniel; Rosselló Móra, Ramon; Rasko, Dave A.; Canto Fuentes, Felipe Antonio del; Vidal Álvarez, Roberto Mauricio (MDPI, 2022)Adherent-invasive E. coli (AIEC) is a pathotype associated with the etiopathogenesis of Crohn’s disease (CD), albeit with an as-yet unclear role. The main pathogenic mechanisms described for AIEC are adherence to epithelial ...
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Gomes, Tania A. T.; Dobrindt, Ulrich; Farfán Urzúa, Mauricio Javier; Piazza, Roxane M. F. (Frontiers Media, 2021)Escherichia coli live as commensals in the intestines of humans and warm-blooded animals (Leimbach et al., 2013). Although most E. coli strains rarely produce disease in healthy individuals, pathogenic strains can cause ...
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Miliwebsky, Elizabeth; Jure, María Ángela; Farfán Urzúa, Mauricio Javier; Palermo, Marina Sandra (Springer, 2023)The composition of gut microbiota (GM) plays a key role in the defense against pathogenic species of Escherichia coli, such as enterohemorrhagic E. coli (EHEC) and enteropathogenic E. coli (EPEC). The symbiotic relationship ...
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Izquierdo, Mariana; Alvestegui, Alejandra; Nataro, James P.; Ruiz Pérez, Fernando; Farfán Urzúa, Mauricio Javier (Hindawi Publishing Corporation, 2014)Adherence to the intestinal epithelia is a key feature in enteroaggregative Escherichia coli (EAEC) infection. The aggregative adherence fimbriae (AAFs) are involved in EAEC interaction with receptors at the surface of ...
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Peña, Mónica; Ampuero Martínez, Manuel Andrés; Garcés, Carlos; Gaggero Brillouet, Aldo Andres; García, Patricia; Velásquez, María Soledad; Luza, Ricardo; Álvarez, Pía; Paredes, Fabio; Acevedo, Johanna; Farfán Urzúa, Mauricio Javier; Solari, Sandra; Soto Rifo, Ricardo Andrés; Valiente Echeverría, Fernando Andrés (Elsevier, 2021)Screening, testing and contact tracing plays a pivotal role in control of the COVID-19 pandemic. To enable this it is necessary to increase the testing capacity. This study compared a SARS-CoV-2 rapid antigen test (RAT) ...
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Pérez Alzola, Luz Patricia; Farfán Urzúa, Mauricio Javier; González Hormazábal, Patricio; Garay, Marta; Olmedo, María Isabel; Ellahueñe Manquian, Manuel; Last, Jerold A. (2004-07)The alkaline single-cell gel electrophoresis (SCGE) assay, also called the comet assay, is a rapid and simple method for the detection of DNA damage in individual cells. The objective of this study was to establish if ...
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Farfán Urzúa, Mauricio Javier; Salas, Carolina; Canales López, Cristina; Silva, Felipe; Villarroel, Milena; Kopp, Katherine; Torres Torretti, Juan Pablo; Santolaya de Pablo, María Elena; Morales, Jorge (BioMed Central, 2014)Background: Mercaptopurine (6-MP) plays a pivotal role in treatment of childhood acute lymphoblastic leukemia (ALL); however, interindividual variability in toxicity of this drug due to genetic polymorphism in 6-MP ...
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Salas Palma, Carolina (Universidad de ChileCyberDocs, 2010)
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Torres Torretti, Juan Pablo; Kors, Lisette; Villarroel, Milena; Piemonte, Paula; Izquierdo, Giannina; Salgado, Carmen; Contardo Pérez, María Verónica; Farfán Urzúa, Mauricio Javier; Maza León, Verónica de la (2016)Background: Respiratory viral infections in episodes of fever and neutropenia (FN) in children with cancer are not well characterized. We compared the clinical outcome of infections caused by different respiratory viruses ...
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Acevedo Muñoz, William; Benadof Fuentes, Dona Nurith; Farfán Urzúa, Mauricio Javier (Soc chilena Infectología, 2021)